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Protein Overview: MDE1

General Information:
Name(s) found: MDE1 / YJR024C [SGD]
Description(s) found:
Found 37 descriptions.
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  • 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 244 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQDVLIHS DDPCHPANLI CTLCKQFFHN NWCTGTGGGI SIKDPNTNYY YLAPSGVQKE  60
   61 KMIPEDLFVM DAQTLEYLRS PKLYKPSACT PLFLACYQKK NAGAIIHTHS QNAVICSLLF 120
  121 GDEFRIANIE QIKAIPSGKV DPVTKKPMAL SFFDTLKIPI IENMAHEDEL IDDLHKTFKD 180
  181 YPDTCAVIVR RHGIFVWGPT IDKAKIFNEA IDYLMELAIK MYQMGIPPDC GIGEEKKHLK 240
  241 MASP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MDE1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..244] PSI-BLAST 129.0 L-ribulose-5-phosphate 4-epimerase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • catalytic activity
    		•  1.58067730905989 bayes_pls_golite062009
  • protein binding
    		•  0.401574215469404 bayes_pls_golite062009
  • lyase activity
    		•  0.114082266751758 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle