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Protein Overview: FBP26

General Information:
Name(s) found: FBP26 / YJL155C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Fructose-2,6-bisphosphatase, required for glucose metabolism [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 452 amino acids

    Gene Ontology:
    Cellular Component: cytosol [TAS]
    Biological Process: glucose metabolic process [IMPLink to PubMed article]
    Molecular Function: fructose-2,6-bisphosphate 2-phosphatase activity [IMPLink to PubMed article]
    [NOT]6-phosphofructo-2-kinase activity [ISSLink to PubMed article][NASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYSTISNDN DIKVCVIMVG LPARGKSFIS QKIIRYLSWL SIKAKCFNVG NYRRDVSGNV  60
   61 PMDAEFFNFE NTDNFKLREL AAQNAIKDIV NFFTKEDGSV AVFDATNSTR KRRKWLKDIC 120
  121 EKNNIQPMFL ESWSNDHELI INNAKDIGST SPDYENSEPH VAEADFLERI RQYERFYEPL 180
  181 DPQKDKDMTF IKLVNIIEEV VINKIRTYLE SRIVFYVMNI RPKPKYIWLS RHGESIYNVE 240
  241 KKIGGDSSLS ERGFQYAKKL EQLVKESAGE INLTVWTSTL KRTQQTANYL PYKKLQWKAL 300
  301 DELDAGVCDG MTYEEIEKEY PEDFKARDND KYEYRYRGGE SYRDVVIRLE PVIMELERQE 360
  361 NVLIITHQAV LRCIYAYFMN VPQEESPWMS IPLHTLIKLE PRAYGTKVTK IKANIPAVST 420
  421 YKEKGTSQVG ELSQSSTKLH QLLNDSPLED KF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) FBP26 YLR345W
    View Details Krogan NJ, et al. (2006) FBP26 STE13 YLR345W
    View Details Gavin AC, et al. (2006) FBP26 YLR345W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data FBP26 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..222] PSI-BLAST 1254.0 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain
    2 View Details [223..452] PSI-BLAST 1254.0 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle