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Protein Overview: ARG2

General Information:
Name(s) found: ARG2 / YJL071W [SGD]
Description(s) found:
Found 30 descriptions.
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  • Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine; forms a complex with Arg5,6p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 574 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [IDALink to PubMed article]
    Biological Process: arginine biosynthetic process [TASLink to PubMed article]
    ornithine biosynthetic process [IMPLink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    Molecular Function: acetyl-CoA:L-glutamate N-acetyltransferase activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWRRIFAHEL KYDQPNASSK NLILSVLNTT ATKREAKDYL SKYTNDSGQH NHCLFFIRDL  60
   61 HKVAPAILSQ FSSVIKRLGM LGLRPMFVIP PSPTHVNIQA ELLDSIVTEA DLKPLHLKEG 120
  121 LTKSRTGLYH SVFSQESRFF DIGNSNFIPI VKPYVYNEET ASEFMTKDVV KFMDCLCQGN 180
  181 IPHIDKFFIL NNAGGIPSGE RNDNAHVFIN LSQELEHLSS SLSHNISTLT KREPRSQNLL 240
  241 HRMEVYVKKD EISSLECEYH DHLENLLLMD KVLSNLAATA TGLITTVKAA ALSSDRKNPL 300
  301 VYNLLTDRSL ISSSLPRFKK KDGEIDSPAN MFDDHAWYEL PSQQVNAAPS NSDAVLVTTV 360
  361 LKKGVHIKTY DYKTLTQFNS IGLPKKFHVP EKGAKPSSNS PKLDINKFKS IIDQSFKRSL 420
  421 DLHDYIKRIN GKIATIIVIG DYEGIAILTY EGSEENSFVY LDKFAVLPHL KGSLGISDII 480
  481 FNLMFKKFPN EILWRSRKDN VVNKWYFQRS VAVLDLSIDL DPEHCDEKQS QFKLFYYGNP 540
  541 QYAKRALRDK KRLREFMRSV RDIKPSWENE KNIS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ARG2 ARG8 CIT1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ARG2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..400] deduced N/A No confident structure predictions are available.
    2 View Details [401..574] MSA 6.009974 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle