YRC Public Data Repository - Protein Structure Prediction

Protein:	ARG2
Organism:	Saccharomyces cerevisiae
Length:	574 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARG2.

Description	E-value	Query Range	Subject Range
NAGS_YEAS1 - Amino-acid acetyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain RM11-1a) GN=ARG2 PE=... NAGS_YEAST - Amino-acid acetyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)... ARG2 - Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme that catalyzes the fi...	0.0	[1..574]	[1..574]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[184..567]	[351..704]
NAGS_SCHPO - Amino-acid acetyltransferase, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G... arg6 - acetylglutamate synthase Arg6	0.0	[184..569]	[216..500]
gi\|19338692 - gi\|19338692\|gb\|AAL86770.1\|AF462069_1 N-acetylglutamate synthase [Mus musculus]	4.0E-41	[399..539]	[376..499]
gi\|9105937, gi\|1... - gi\|9105937\|gb\|AAF83811.1\|AE003938_2 acetylglutamate kinase [Xylella fastidiosa 9a5c], gi\|15837603\|re... gi\|11360469 - gi\|11360469\|pir\|\|H82734 acetylglutamate kinase XF1001 [imported] - Xylella fastidiosa (strain 9a5c)	1.0E-37	[403..542]	[302..419]
ARG56_CANAX - Protein ARG5,6, mitochondrial OS=Candida albicans GN=ARG5,6 PE=3 SV=1	2.0E-30	[419..539]	[369..471]
AR56_NEUCR, ARG5... - Protein arg-6, mitochondrial OS=Neurospora crassa GN=arg-6 PE=1 SV=1, (P54898) Arg-6 protein, mitoch... ARG56_NEUCR - Protein arg-6, mitochondrial OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM...	7.0E-28	[422..538]	[367..466]
gi\|4906 - gi\|4906\|emb\|CAA45132.1\| N-acetyl-gamma-glutamyl-phosphate reductase; acetylglutamate kinase [Schizos...	9.0E-27	[421..559]	[378..490]

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Predicted Domain #1

Region A:
Residues: [1-400]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWRRIFAHEL KYDQPNASSK NLILSVLNTT ATKREAKDYL SKYTNDSGQH NHCLFFIRDL  60
   61 HKVAPAILSQ FSSVIKRLGM LGLRPMFVIP PSPTHVNIQA ELLDSIVTEA DLKPLHLKEG 120
  121 LTKSRTGLYH SVFSQESRFF DIGNSNFIPI VKPYVYNEET ASEFMTKDVV KFMDCLCQGN 180
  181 IPHIDKFFIL NNAGGIPSGE RNDNAHVFIN LSQELEHLSS SLSHNISTLT KREPRSQNLL 240
  241 HRMEVYVKKD EISSLECEYH DHLENLLLMD KVLSNLAATA TGLITTVKAA ALSSDRKNPL 300
  301 VYNLLTDRSL ISSSLPRFKK KDGEIDSPAN MFDDHAWYEL PSQQVNAAPS NSDAVLVTTV 360
  361 LKKGVHIKTY DYKTLTQFNS IGLPKKFHVP EKGAKPSSNS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [401-574]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKLDINKFKS IIDQSFKRSL DLHDYIKRIN GKIATIIVIG DYEGIAILTY EGSEENSFVY  60
   61 LDKFAVLPHL KGSLGISDII FNLMFKKFPN EILWRSRKDN VVNKWYFQRS VAVLDLSIDL 120
  121 DPEHCDEKQS QFKLFYYGNP QYAKRALRDK KRLREFMRSV RDIKPSWENE KNIS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits