Protein Overview: TIM54

General Information:
Name(s) found:	TIM54 / YJL054W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6322407\|ref\|NP_012481.1\| Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane; Tim54p [Saccharomyces cerevisiae] [NCBI NR] gi\|1352983\|sp\|P47045.1\|TIM54_YEAST RecName: Full=Mitochondrial import inner membrane translocase subunit TIM54 [NCBI NR] pir\|\|S56826 hypothetical protein YJL054w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1008193\|emb\|CAA89345.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] (P47045) Hypothetical 54.2 kDa protein in BTN1-PEP8 intergenic region [Swiss-Prot] Mitochondrial import inner membrane translocase subunit TIM54 OS=Saccharomyces cerevisiae GN=TIM54 PE=1 SV=1 [Swiss-Prot] TIM54 Translocase for the insertion of proteins into the mitochondrial inner membrane [mips] Component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane [SGD] TIM54, Chr X from 333961-335397 [yeast_orfs2] Chr X from 333961-335397 [yeastorf3.fasta] TIM54 SGDID:S0003590, Chr X from 334181-335617, Verified ORF [yeastflysequest.fasta] Tim54p [Saccharomyces cerevisiae]gi\|1008193\|emb\|CAA89345.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|1077813\|pir\|\|S56826 hypothetical protein YJL054w - yeast (Saccharomyces cerevisiae)gi\|1352983\|sp\|P47045\|YJF4_YEAST Hypothetical 54.2 kDa pr [nrdb_11152004_Chlamydomonas] TIM54 SGDID:S000003590, Chr X from 334181-335617, Verified ORF, "Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] TIM54 SGDID:S000003590, Chr X from 334260-335696, Verified ORF, "Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane" [yeast-contam.fasta] TIM54 SGDID:S000003590, Chr X from 334259-335695, Verified ORF, "Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane" [yeast-200209-contam.fasta] Mitochondrial import inner membrane translocase subunit TIM54 [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane; Tim54p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] TIM54 SGDID:S000003590, Chr X from 334259-335695, Verified ORF, "Component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane" [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta] [chemostatdb.fasta] Mitochondrial import inner membrane translocase subunit TIM54 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TIM54 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] TIM54 SGDID:S000003590, Chr X from 334265-335701, Genome Release 64-1-1, Verified ORF, "Component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane" [yeast-030211-contam.fasta] TIM54 SGDID:S000003590, Chr X from 334265-335701, Genome Release 64-2-1, Verified ORF, "Component of the mitochondrial TIM22 complex; involved in insertion of polytopic proteins into the inner membrane" [20141208_orf_trans.fasta] TR1112\|c0_g1_i1\|g.871 ORF TR1112\|c0_g1_i1\|g.871 TR1112\|c0_g1_i1\|m.871 type:complete len:479 (+) TR1112\|c0_g1_i1:11-1447(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] YJL054W SGDID:S000003590, Chr X from 334265-335701, Genome Release 64-1-1, Verified ORF, "Component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_6303\|g.4358 ORF asmbl_6303\|g.4358 asmbl_6303\|m.4358 type:complete len:479 (+) asmbl_6303:9-1445(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_6296\|g.3828 ORF ID=asmbl_6296\|g.3828 ID=asmbl_6296\|m.3828 type:complete len:479 (+) ID=asmbl_6296:9-1445(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	478 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA] mitochondrial inner membrane protein insertion complex [IDA]
Biological Process:	protein import into mitochondrial inner membrane [IGI][IPI]
Molecular Function:	protein transporter activity [IGI][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSESGKPIA KPIRKPGYTN PALKALGIPA LRLPSRNWMI FWSVLTVSIG GIAYDKYKQR  60
   61 QILSHATDLV KPLAEESMEV DKVPRKITVF IAPPPNDYLE SSLKVWRRYV KPVLYYAGLD 120
  121 YELVQEDRQG IIRTNVANRI RELRKEILAS TDGQPVKEPN QTVAKPSGSS TSKISSLLPF 180
  181 NKIIQDPAEE DDSFDPEIGK KFKENFDWRN VIGIFYTMPK PKHIISEDAL TKDPILSGGV 240
  241 ICLGRGAYKE YIAGIHEGLL GPIEKTEKTG STEPKMTGVV EANQIESKVS ESGATELVDA 300
  301 EKETALEEAK VQDDLKVDEE NSSEDSQKFL KPFISSDQYP DLQIASELQT PNGEFIRNPN 360
  361 TNIPLLINQP LLVIPIPNLI GFTTIPRRIH RFYQKRFYVE DVCSSVVNCV RQTRIRPFDI 420
  421 AKDIDLAKDE EKDWPQNWVK QGKEKNSEWT QELVCDPRIT KHMFVYEKPP KEEPESDI

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		TIM10 TIM12 TIM22 TIM54 TIM9
View Details	Qiu et al. (2008)		MDJ2 PAM16 TIM12 TIM18 TIM22 TIM54

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	TIM54	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..166]	MSA	1.002945	View MSA. No confident structure predictions are available.
2	View Details	[167..339]	deduced	N/A	No confident structure predictions are available.
3	View Details	[340..478]	MSA	1.003959	View MSA. No confident structure predictions are available.

Protein Overview: TIM54

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: