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Protein Overview: MPS3

General Information:
Name(s) found: MPS3 / YJL019W [SGD]
Description(s) found:
Found 10 descriptions.
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  • Nuclear envelope protein required for SPB duplication and nuclear fusion; localizes to the SPB half bridge and at telomeres during meiosis; required with Ndj1p and Csm4p for meiotic bouquet formation and telomere-led rapid prophase movement [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 620 amino acids

    Gene Ontology:
    Cellular Component: half bridge of spindle pole body [IDALink to PubMed article]
    integral to membrane [IDALink to PubMed articleLink to PubMed article]
    Biological Process: mitotic sister chromatid cohesion [IMPLink to PubMed article]
    spindle pole body duplication in nuclear envelope [IMPLink to PubMed article]
    nuclear migration during conjugation with cellular fusion [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNSNEHRRE EAGAANEQMP YNKAVKSAYA DVLKDKMNRE QEISLRAIKK GIYTDGGETD  60
   61 NYDMDKENDS AYEMFKKNLD FPLDQHNDDD DDDPYIEDNG QETDGYSDED YTDEADKSFI 120
  121 EDSDSDSYDL ESNSDFEENL ESSGEAKKLK WRTYIFYGGL FFVFYFFGSF LMTTVKNNDL 180
  181 ESHSSGATSS PGKSFSNLQK QVNHLYSELS KRDEKHSSEL DKTVKIIVSQ FEKNIKRLLP 240
  241 SNLVNFENDI NSLTKQVETI STSMSELQRR NHKFTVENVT QWQDQLVKQL DTHLPQEIPV 300
  301 VINNSSSLLI IPELHNYLSA LISDVIESPG IGTAGSAESR WEYDLNRYVK EILSNELQYI 360
  361 DKDYFIQEMN RRLQSNKQEI WEEITNRLET QQQQQQQQVQ QDYSNVPQQY SSILMKRLIH 420
  421 QIYNSNQHQW EDDLDFATYV QGTKLLNHLT SPTWRQGSGV QPIELLTDSK QSSSTYWQCE 480
  481 NEPGCSWAIR FKTPLYLTKI SYMHGRFTNN LHIMNSAPRL ISLYVKLSQT KEIKALQTLA 540
  541 NQYGFGQHHK RDRNYIKIAK FEYRLTDSRI RQQMYLPPWF IQLKPLVRSI VFQVDENYGN 600
  601 KKFISLRKFI INGVTPQICK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..110] deduced N/A No confident structure predictions are available.
    2 View Details [111..425] ORFEUS 7.13 GAP related domain of neurofibromin
    3 View Details [426..620] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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