Protein Overview: YPS6

General Information:
Name(s) found:	YPS6 / YIR039C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|731925\|sp\|P40583.1\|YPS6_YEAST RecName: Full=Aspartic proteinase yapsin-6; Flags: Precursor [NCBI NR] gi\|6322230\|ref\|NP_012305.1\| Putative GPI-anchored aspartic protease; Yps6p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S50344 aspergillopepsin homolog YIR039c - yeast (Saccharomyces cerevisiae) [NCBI NR] Aspartic proteinase yapsin-6 OS=Saccharomyces cerevisiae GN=YPS6 PE=1 SV=1 [Swiss-Prot] (P40583) Putative aspartyl protease YIR039C precursor (EC 3.4.23.-) [Swiss-Prot] YPS6 GPI-anchored aspartic protease (Yapsin 6) [mips] Putative GPI-anchored aspartic protease [SGD] YPS6, Chr IX from 430494-432107, reverse complement [yeast_orfs2] Chr IX from 430494-432107, reverse complement [yeastorf3.fasta] Chr IX from 432107-430494, reverse complement [yeastorf5.fasta] YPS6 SGDID:S0001478, Chr IX from 432107-430494, reverse complement, Verified ORF [yeastflysequest.fasta] Putative GPI-anchored aspartic protease [Saccharomyces cerevisiae]gi\|2131184\|pir\|\|S50344 aspergillopepsin homolog YIR039c - yeast (Saccharomyces cerevisiae)gi\|731925\|sp\|P40583\|YIV9_YEAST Putative aspartyl protease YIR039C precursor [nrdb_11152004_Chlamydomonas] YPS6 SGDID:S000001478, Chr IX from 432107-430494, reverse complement, Verified ORF, "Putative GPI-anchored aspartic protease" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Aspartic proteinase yapsin-6 precursor [nr-271106-contam.fasta] Putative GPI-anchored aspartic protease; Yps6p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Aspartic proteinase yapsin-6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPS6 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YPS6 SGDID:S000001478, Chr IX from 432111-430498, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance" [yeast-030211-contam.fasta] YPS6 SGDID:S000001478, Chr IX from 432111-430498, Genome Release 64-2-1, reverse complement, Verified ORF, "Putative GPI-anchored aspartic protease; member of the yapsin family of proteases involved in cell wall growth and maintenance" [20141208_orf_trans.fasta] YIR039C SGDID:S000001478, Chr IX from 432111-430498, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	537 amino acids
Gene Ontology:
Cellular Component:	fungal-type cell wall [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	aspartic-type endopeptidase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLISILSLL SSLMCSLTVL GSSASSYVKF PVQKLADIIN ICTQDVSTVF KRNEVLNTTV  60
   61 INGIGVYVVK MEIGTPPQTL YLQLDTGSSD MIVNNADIAY CKSMSDGSDY ASTDNYELTA 120
  121 TFNGLPSTTI SSEAYNTLCS YWGTFDASNS STFENNATFF NNTYGDGTYY AGTYGTDVVS 180
  181 FENITLNDFT FGVSNDTIGN PSGILGISLP IAEFTDGIEY ALALNRTPFI YDNFPMELKN 240
  241 QGKINKIAYS LFLNGPDAHF GSILFGAVDK SKYTGQLYTL PMLQAFNTLG SNPGMIITAQ 300
  301 SVAILDSESG NKTVSDIQFP VMLDSGTTFS YLPTEIAEAI GKSFDGEYSS DDQGYIFDCS 360
  361 KVNDTLLSVD FGGFNISANI SNFVTSAKDR CVLNVKQSES TYMLGDAFLV DAYVVYDLEN 420
  421 YEISIAQASF NNQEEDIEVI SDTVPGATPA PGYFSTWVYK PGSPIGTGDF INVSWTSYSE 480
  481 FSQYKSLLAT AAQSDDASSF SSSGGSSEST TKKQNAGYKY RSSFSFSLLS FISYFLL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RGT2	YPS6	2	Unpublished Fields Lab Data
View Screen	BOI2	YPS6	2	Unpublished Fields Lab Data
View Screen	ROM2	YPS6	2	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..68] [245..281] [411..451]	PSI-BLAST	553.38764	No description for 1ypsA_ was found.
2	View Details	[69..244] [282..410]	PSI-BLAST	553.38764	No description for 1ypsA_ was found.
3	View Details	[452..537]	deduced	N/A	No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
aspartic-type endopeptidase activity	7.68175187751599	bayes_pls_golite062009
aspartic-type peptidase activity	7.68175187751599	bayes_pls_golite062009
peptidase activity	3.09986068674657	bayes_pls_golite062009
endopeptidase activity	3.08503547117772	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	2.89367142096521	bayes_pls_golite062009
hydrolase activity	2.46470106080415	bayes_pls_golite062009
catalytic activity	1.54514410489082	bayes_pls_golite062009
binding	0.742107862879277	bayes_pls_golite062009
protein binding	0.401296299316154	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2