Protein Overview: DAL1

General Information:
Name(s) found:	DAL1 / YIR027C [SGD]
Description(s) found: Found 23 descriptions. SHOW ALL	Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression [SGD]
Organism:	Saccharomyces cerevisiae
Length:	460 amino acids
Gene Ontology:
Cellular Component:	intracellular [IC]
Biological Process:	allantoin catabolic process [IGI][IMP][ISS]
Molecular Function:	allantoinase activity [IMP][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPINAITSDH VIINGANKPA TIVYSTESGT ILDVLEGSVV MEKTEITKYE IHTLENVSPC  60
   61 TILPGLVDSH VHLNEPGRTS WEGFETGTQA AISGGVTTVV DMPLNAIPPT TNVENFRIKL 120
  121 EAAEGQMWCD VGFWGGLVPH NLPDLIPLVK AGVRGFKGFL LDSGVEEFPP IGKEYIEEAL 180
  181 KVLAEEDTMM MFHAELPKAH EDQQQPEQSH REYSSFLSSR PDSFEIDAIN LILECLRARN 240
  241 GPVPPVHIVH LASMKAIPLI RKARASGLPV TTETCFHYLC IAAEQIPDGA TYFKCCPPIR 300
  301 SESNRQGLWD ALREGVIGSV VSDHSPCTPE LKNLQKGDFF DSWGGIASVG LGLPLMFTQG 360
  361 CSLVDIVTWC CKNTSHQVGL SHQKGTIAPG YDADLVVFDT ASKHKISNSS VYFKNKLTAY 420
  421 NGMTVKGTVL KTILRGQVVY TNANGVSKTP LGQTLLDSRR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	SNP1	DAL1	1	Unpublished Fields Lab Data
View Screen	SPT21	DAL1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..460]	PSI-BLAST	435.154902	L-hydantoinase

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
allantoinase activity	2.45571277189844	bayes_pls_golite062009
dihydroorotase activity	2.32070383330692	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2.20489529944693	bayes_pls_golite062009
hydrolase activity	2.17584977880576	bayes_pls_golite062009
dihydropyrimidinase activity	2.07436350152924	bayes_pls_golite062009
deaminase activity	1.79186203771221	bayes_pls_golite062009
catalytic activity	1.70199291046899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.60895003474033	bayes_pls_golite062009
adenine deaminase activity	1.00917389012319	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.573107361273483	bayes_pls_golite062009
AMP deaminase activity	0.137175704459036	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2