Protein Overview: SUC2

General Information:
Name(s) found:	SUC2 / YIL162W [SGD]
Description(s) found: SHOW ONLY BEST	pir\|\|IFBY beta-fructofuranosidase (EC 3.2.1.26) 2 precursor - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|6322029\|ref\|NP_012104.1\| Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively; Suc2p [Saccharomyces cerevisiae] [NCBI NR] gi\|600815\|emb\|CAA87030.1\| invertase [Saccharomyces cerevisiae] [NCBI NR] gi\|3834\|emb\|CAA24618.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|124703\|sp\|P00724.1\|INV2_YEAST RecName: Full=Invertase 2; AltName: Full=Beta-fructofuranosidase 2; AltName: Full=Saccharase; Flags: Precursor [NCBI NR] Invertase 2 OS=Saccharomyces cerevisiae GN=SUC2 PE=1 SV=1 [Swiss-Prot] SUC2 Invertase (sucrose hydrolyzing enzyme) [mips] Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively [SGD] SUC2, Chr IX from 37385-38983 [yeast_orfs2] Chr IX from 37385-38983 [yeastorf3.fasta] (P00724) Invertase 2 precursor (EC 3.2.1.26) (Beta-fructofuranosidase 2) (Saccharase) [4932.FASTACCERV.txt] SUC2 SGDID:S0001424, Chr IX from 37385-38983, Verified ORF [yeastflysequest.fasta] Suc2p [Saccharomyces cerevisiae]gi\|3834\|emb\|CAA24618.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|600815\|emb\|CAA87030.1\| invertase [Saccharomyces cerevisiae]gi\|67498\|pir\|\|IFBY beta-fructofuranosidase (EC 3.2.1.26) 2 precursor - yeast (Sacch [nrdb_11152004_Chlamydomonas] SUC2 SGDID:S000001424, Chr IX from 37385-38983, Verified ORF, "Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] invertase [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively; Suc2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Invertase 2 precursor (Beta-fructofuranosidase 2) (Saccharase) [nr-271106-contam.fasta] [chemostatdb.fasta] Invertase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SUC2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SUC2 SGDID:S000001424, Chr IX from 37385-38983, Genome Release 64-1-1, Verified ORF, "Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively" [yeast-030211-contam.fasta] SUC2 SGDID:S000001424, Chr IX from 37385-38983, Genome Release 64-2-1, Verified ORF, "Invertase; sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively" [20141208_orf_trans.fasta] YIL162W SGDID:S000001424, Chr IX from 37385-38983, Genome Release 64-1-1, Verified ORF, "Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	532 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] mitochondrion [IDA ] extracellular region [IDA]
Biological Process:	sucrose catabolic process [TAS]
Molecular Function:	beta-fructofuranosidase activity [IDA ][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLQAFLFLL AGFAAKISAS MTNETSDRPL VHFTPNKGWM NDPNGLWYDE KDAKWHLYFQ  60
   61 YNPNDTVWGT PLFWGHATSD DLTNWEDQPI AIAPKRNDSG AFSGSMVVDY NNTSGFFNDT 120
  121 IDPRQRCVAI WTYNTPESEE QYISYSLDGG YTFTEYQKNP VLAANSTQFR DPKVFWYEPS 180
  181 QKWIMTAAKS QDYKIEIYSS DDLKSWKLES AFANEGFLGY QYECPGLIEV PTEQDPSKSY 240
  241 WVMFISINPG APAGGSFNQY FVGSFNGTHF EAFDNQSRVV DFGKDYYALQ TFFNTDPTYG 300
  301 SALGIAWASN WEYSAFVPTN PWRSSMSLVR KFSLNTEYQA NPETELINLK AEPILNISNA 360
  361 GPWSRFATNT TLTKANSYNV DLSNSTGTLE FELVYAVNTT QTISKSVFAD LSLWFKGLED 420
  421 PEEYLRMGFE VSASSFFLDR GNSKVKFVKE NPYFTNRMSV NNQPFKSEND LSYYKVYGLL 480
  481 DQNILELYFN DGDVVSTNTY FMTTGNALGS VNMTTGVDNL FYIDKFQVRE VK

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		EKI1 RTC3 SUC2
View Details	Qiu et al. (2008)		CTS1 PGU1 SUC2

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	AIM13	SUC2	1	Unpublished Fields Lab Data
View Screen	MET30	SUC2	1	Unpublished Fields Lab Data
View Screen	CTF13	SUC2	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..532]	PSI-BLAST	85.154902	The three-dimensional structure of beta-fructosidase (invertase) from Thermotoga maritima

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
beta-fructofuranosidase activity	7.66330112409449	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	4.84901331389046	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	4.12404022449559	bayes_pls_golite062009
hydrolase activity	2.77015860151809	bayes_pls_golite062009
carbohydrate binding	1.95748400706644	bayes_pls_golite062009
binding	1.30052601179082	bayes_pls_golite062009
sugar binding	1.05545473249163	bayes_pls_golite062009
catalytic activity	0.925574609957366	bayes_pls_golite062009
protein binding	0.0138714145421778	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2