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Protein Overview: REV7

General Information:
Name(s) found: REV7 / YIL139C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Accessory subunit of DNA polymerase zeta, involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 245 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    zeta DNA polymerase complex [IDALink to PubMed article]
    Biological Process: mutagenesis [TASLink to PubMed article]
    DNA repair [TASLink to PubMed article]
    Molecular Function: DNA-directed DNA polymerase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRWVEKWLR VYLKCYINLI LFYRNVYPPQ SFDYTTYQSF NLPQFVPINR HPALIDYIEE  60
   61 LILDVLSKLT HVYRFSICII NKKNDLCIEK YVLDFSELQH VDKDDQIITE TEVFDEFRSS 120
  121 LNSLIMHLEK LPKVNDDTIT FEAVINAIEL ELGHKLDRNR RVDSLEEKAE IERDSNWVKC 180
  181 QEDENLPDNN GFQPPKIKLT SLVGSDVGPL IIHQFSEKLI SGDDKILNGV YSQYEEGESI 240
  241 FGSLF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) REV3 REV7
    View Details Qiu et al. (2008) DPB3 POL3 POL31 POL32 REV3 REV7

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen VPS64 REV7 1 Unpublished Fields Lab Data
    View Screen YKL171W REV7 1 Unpublished Fields Lab Data
    View Screen CUS1 REV7 1 Unpublished Fields Lab Data
    View Screen PSF3 REV7 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..245] Pfam 86.408935 HORMA domain No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.10837785003329 bayes_pls_golite062009
  • protein binding
    		•  0.566223135676065 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle