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Protein Overview: SIM1

General Information:
Name(s) found: SIM1 / YIL123W [SGD]
Description(s) found:
Found 18 descriptions.
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  • Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 475 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed article]
    Biological Process: microtubule cytoskeleton organization [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSTAVTTL ISSGAIVSAL PHVDVHQEDA HQHKRAVAYK YVYETVVVDS DGHTVTPAAS  60
   61 EVATAATSAI ITTSVLAPTS SAAAGIAASI AVSSAALAKN EKISDAAASA TASTSQGASS 120
  121 SSSSSSATST LESSSVSSSS EEAAPTSTVV STSSATQSSA SSATKSSTSS TSPSTSTSTS 180
  181 TSSTSSSSSS SSSSSSSSSG SGSIYGDLAD FSGPSEKFQD GTIPCDKFPS GQGVISIDWI 240
  241 GEGGWSGVEN TDTSTGGSCK EGSYCSYSCQ PGMSKTQWPS DQPSDGRSVG GLLCKNGYLY 300
  301 RSNTDADYLC EWGVEAAYVV SKLSKGVAIC RTDYPGTENM VIPTYVEGGS SLPLTVVDQD 360
  361 TYFTWEGKKT SAQYYVNNAG VSVEDGCIWG TSGSGIGNWA PLNFGAGSTG GVTYLSLIPN 420
  421 PNNSDALNYN VKIVAADDSS NVIGECVYEN GEFSGGADGC TVSVTSGKAH FVLYN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SIM1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..199] ab initio 13.03 No description for 1m2vB was found.
    2 View Details [200..339] PSI-BLAST 2.09691 Fibrinogen
    3 View Details [340..475] Pfam 39.79588 Beta-glucosidase (SUN family) No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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