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Protein Overview: CBR1

General Information:
Name(s) found: CBR1 / YIL043C [SGD]
Description(s) found:
Found 19 descriptions.
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  • Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 322 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    microsome [IDALink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article]
    Biological Process: electron transport [IDALink to PubMed article]
    Molecular Function: cytochrome-b5 reductase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYKYSYYIRR KNEREKKVLK VCIQLALQQE TQSIKQSKMA IDAQKLVVVI VIVVVPLLFK  60
   61 FIIGPKTKPV LDPKRNDFQS FPLVEKTILT HNTSMYKFGL PHADDVLGLP IGQHIVIKAN 120
  121 INGKDITRSY TPTSLDGDTK GNFELLVKSY PTGNVSKMIG ELKIGDSIQI KGPRGNYHYE 180
  181 RNCRSHLGMI AGGTGIAPMY QIMKAIAMDP HDTTKVSLVF GNVHEEDILL KKELEALVAM 240
  241 KPSQFKIVYY LDSPDREDWT GGVGYITKDV IKEHLPAATM DNVQILICGP PAMVASVRRS 300
  301 TVDLGFRRSK PLSKMEDQVF VF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen ERG12 CBR1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..72] PSI-BLAST 9.39794 2Fe-2S ferredoxin
    2 View Details [73..174] PSI-BLAST 469.9897 Nitrate reductase core domain; Nitrate reductase
    3 View Details [175..322] PSI-BLAST 469.9897 Nitrate reductase core domain; Nitrate reductase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle