Protein Overview: FAA3

General Information:
Name(s) found:	FAA3 / YIL009W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|729925\|sp\|P39002.1\|LCF3_YEAST RecName: Full=Long-chain-fatty-acid--CoA ligase 3; AltName: Full=Long-chain acyl-CoA synthetase 3; AltName: Full=Fatty acid activator 3 [NCBI NR] gi\|6322182\|ref\|NP_012257.1\| Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; Faa3p [Saccharomyces cerevisiae] [NCBI NR] gi\|558394\|emb\|CAA86241.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|473141\|emb\|CAA82755.1\| fatty acid activator 3 [Saccharomyces cerevisiae] [NCBI NR] gi\|45270110\|gb\|AAS56436.1\| YIL009W [Saccharomyces cerevisiae] [NCBI NR] pir\|\|B54901 long-chain-fatty-acid-CoA ligase (EC 6.2.1.3) FAA3 - yeast (Saccharomyces cerevisiae) [NCBI NR] Long-chain-fatty-acid--CoA ligase 3 OS=Saccharomyces cerevisiae GN=FAA3 PE=1 SV=1 [Swiss-Prot] FAA3 Acyl CoA synthase [mips] Long chain fatty acyl-CoA synthetase, activates imported fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery [SGD] FAA3, Chr IX from 339341-341425 [yeast_orfs2] Chr IX from 339341-341425 [yeastorf3.fasta] (P39002) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 3) (Fatty acid activator 3) [4932.FASTACCERV.txt] FAA3 SGDID:S0001271, Chr IX from 339341-341425, Verified ORF [yeastflysequest.fasta] Faa3p [Saccharomyces cerevisiae]gi\|473141\|emb\|CAA82755.1\| fatty acid activator 3 [Saccharomyces cerevisiae]gi\|558394\|emb\|CAA86241.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|45270110\|gb\|AAS56436.1\| YIL009W [Saccharomyces cerevisiae]gi\|1078 [nrdb_11152004_Chlamydomonas] FAA3 SGDID:S000001271, Chr IX from 339341-341425, Verified ORF, "Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] fatty acid activator 3 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YIL009W [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Long-chain-fatty-acid--CoA ligase 3 (Long-chain acyl-CoA synthetase 3) (Fatty acid activator 3) [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; Faa3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Long-chain-fatty-acid--CoA ligase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FAA3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] FAA3 SGDID:S000001271, Chr IX from 339344-341428, Genome Release 64-1-1, Verified ORF, "Long chain fatty acyl-CoA synthetase, activates imported fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" [yeast-030211-contam.fasta] FAA3 SGDID:S000001271, Chr IX from 339344-341428, Genome Release 64-2-1, Verified ORF, "Long chain fatty acyl-CoA synthetase; activates imported fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" [20141208_orf_trans.fasta] YIL009W SGDID:S000001271, Chr IX from 339344-341428, Genome Release 64-1-1, Verified ORF, "Long chain fatty acyl-CoA synthetase, activates imported fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	694 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	lipid metabolic process [IGI][IMP] N-terminal protein myristoylation [IGI][IMP]
Molecular Function:	long-chain fatty acid-CoA ligase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEQHSVAVG KAANEHETAP RRNVRVKKRP LIRPLNSSAS TLYEFALECF NKGGKRDGMA  60
   61 WRDVIEIHET KKTIVRKVDG KDKSIEKTWL YYEMSPYKMM TYQELIWVMH DMGRGLAKIG 120
  121 IKPNGEHKFH IFASTSHKWM KIFLGCISQG IPVVTAYDTL GESGLIHSMV ETESAAIFTD 180
  181 NQLLAKMIVP LQSAKDIKFL IHNEPIDPND RRQNGKLYKA AKDAINKIRE VRPDIKIYSF 240
  241 EEVVKIGKKS KDEVKLHPPE PKDLACIMYT SGSISAPKGV VLTHYNIVSG IAGVGHNVFG 300
  301 WIGSTDRVLS FLPLAHIFEL VFEFEAFYWN GILGYGSVKT LTNTSTRNCK GDLVEFKPTI 360
  361 MIGVAAVWET VRKAILEKIS DLTPVLQKIF WSAYSMKEKS VPCTGFLSRM VFKKVRQATG 420
  421 GHLKYIMNGG SAISIDAQKF FSIVLCPMII GYGLTETVAN ACVLEPDHFE YGIVGDLVGS 480
  481 VTAKLVDVKD LGYYAKNNQG ELLLKGAPVC SEYYKNPIET AVSFTYDGWF RTGDIVEWTP 540
  541 KGQLKIIDRR KNLVKTLNGE YIALEKLESV YRSNSYVKNI CVYADESRVK PVGIVVPNPG 600
  601 PLSKFAVKLR IMKKGEDIEN YIHDKALRNA VFKEMIATAK SQGLVGIELL CGIVFFDEEW 660
  661 TPENGFVTSA QKLKRREILA AVKSEVERVY KENS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#02 Alpha Factor Prep1-TiO2 enriched, new search criteria	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	ILM1	FAA3	1	Lockshon D, et al. (2006)

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	FAA3	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..63] [88..100] [267..550]	PSI-BLAST	264.228787	Luciferase
2	View Details	[64..87] [101..266] [551..694]	PSI-BLAST	264.228787	Luciferase

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.86

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2