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Protein Overview: WSS1

General Information:
Name(s) found: WSS1 / YHR134W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Sumoylated protein of unknown function, identified based on genetic interactions with SMT3; UV-sensitive mutant phenotype and genetic interactions suggest a role in the DNA damage response, processing stalled or collapsed replication forks [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 269 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: protein sumoylation [IGILink to PubMed article]
    response to UV-C [IMPLink to PubMed articleLink to PubMed article]
    response to DNA damage stimulus [IGILink to PubMed article]
    response to UV-B [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTEGIKSPS AKYHDMAGSQ RIPHKNPHIQ KVAVLQSKPN KEDALNLIKE IAHKVSYLMK  60
   61 ENHFKVTNLV EFYPRDQRLL GMNVNHGSKI MLRLRCSTDE FQFLPMECIM GTMLHELTHN 120
  121 LFGPHDKKFY NKLDELIGRQ WVIEQRGLYD TFLGNGQRLG GRANLRSNRY PMTGISTNTG 180
  181 IVRKRGKGVK LGSLHPEGIS SIDRGNSPRE LAAFAAERRY RDDRWCGETK NNKDQIISDN 240
  241 ISSSLEVVIL DDDDEVLPGD TLIEVIDLT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #22 Asynchronous Prep2-IMAC Phosphopeptide enrichment B1-2 Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] MSA 3.008966 View MSA. No confident structure predictions are available.
    2 View Details [187..269] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle