Protein Overview: NOP10

General Information:
Name(s) found:	NOP10 / YHR072W-A [SGD]
Description(s) found: SHOW ONLY BEST	gi\|83753708\|pdb\|1Y2Y\|A Chain A, Structural Characterization Of Nop10p Using Nuclear Magnetic Resonance Spectroscopy [NCBI NR] gi\|7839181\|ref\|NP_058135.1\| Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA; Nop10p [Saccharomyces cerevisiae] [NCBI NR] gi\|7493868\|pir\|\|S78745 protein YHR072w-a - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|54036193\|sp\|Q6Q547.1\|NOP10_YEAST RecName: Full=H/ACA ribonucleoprotein complex subunit 3; AltName: Full=Nucleolar protein family A member 3; AltName: Full=snoRNP protein NOP10; AltName: Full=Nucleolar protein 10 [NCBI NR] gi\|45270986\|gb\|AAS56874.1\| YHR072W-A [Saccharomyces cerevisiae] [NCBI NR] H/ACA ribonucleoprotein complex subunit 3 OS=Saccharomyces cerevisiae GN=NOP10 PE=1 SV=1 [Swiss-Prot] (Q6Q547) Ribosome biogenesis protein Nop10 [Swiss-Prot] NOP10 Nucleolar rRNA processing protein [mips] Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA [SGD] NOP10, Chr VIII from 241665-241841 [yeast_orfs2] Chr VIII from 241665-241841 [yeastorf3.fasta] NOP10 SGDID:S0007455, Chr VIII from 241665-241841, Verified ORF [yeastflysequest.fasta] Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA [Saccharomyces cerevisiae]gi\|7493868\|pir\|\|S78745 protein YHR072w-a - yeast (Saccharomyces ce [nrdb_11152004_Chlamydomonas] NOP10 SGDID:S000007455, Chr VIII from 241666-241842, Verified ORF, "Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Chain A, Structural Characterization Of Nop10p Using Nuclear Magnetic Resonance Spectroscopy [nr-271106-contam.fasta] YHR072W-A [Saccharomyces cerevisiae] [nr-271106-contam.fasta] protein YHR072w-a - yeast (Saccharomyces cerevisiae) [nr-271106-contam.fasta] H/ACA ribonucleoprotein complex subunit 3 (Nucleolar protein family A member 3) (snoRNP protein NOP10) [nr-271106-contam.fasta] Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA; Nop10p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] H/ACA ribonucleoprotein complex subunit 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOP10 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] NOP10 SGDID:S000007455, Chr VIII from 241664-241840, Genome Release 64-1-1, Verified ORF, "Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA" [yeast-030211-contam.fasta] NOP10 SGDID:S000007455, Chr VIII from 241664-241840, Genome Release 64-2-1, Verified ORF, "Subunit of box H/ACA snoRNP complex; required for pseudouridylation and processing of pre-18S rRNA" [20141208_orf_trans.fasta] YHR072W-A SGDID:S000007455, Chr VIII from 241664-241840, Genome Release 64-1-1, Verified ORF, "Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	58 amino acids
Gene Ontology:
Cellular Component:	nuclear outer membrane [TAS] small nucleolar ribonucleoprotein complex [IPI]
Biological Process:	rRNA modification [TAS] rRNA pseudouridine synthesis [IMP]
Molecular Function:	RNA binding [IDA]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MHLMYTLGPD GKRIYTLKKV TESGEITKSA HPARFSPDDK YSRQRVTLKK RFGLVPGQ

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		GAR1 LUG1 NHP2 NOP10
View Details	Krogan NJ, et al. (2006)		COQ10 DBP3 DSE4 GAR1 KRI1 KRR1 NHP2 NOP10 NOP6 YCR016W YDR381C-A
View Details	Qiu et al. (2008)		NHP2 NOP10

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

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No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	NOP10	Huh WK, et al. (2003)
View Data	NOP10 and NOP56	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..58]	deduced	N/A	Confident ab initio structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
RNA binding	3.61380698450754	bayes_pls_golite062009
nucleic acid binding	2.36306971710899	bayes_pls_golite062009
binding	2.07200237133183	bayes_pls_golite062009
protein binding	0.377070376016177	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle