Protein Overview: BCD1

General Information:
Name(s) found:	BCD1 / YHR040W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|731652\|sp\|P38772.1\|YHK0_YEAST RecName: Full=Zinc finger protein YHR040W [NCBI NR] gi\|6321830\|ref\|NP_011906.1\| Essential protein required for the accumulation of box C/D snoRNA; Bcd1p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S46736 hypothetical protein YHR040w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|488170\|gb\|AAB68905.1\| Yhr040wp [Saccharomyces cerevisiae] [NCBI NR] Zinc finger protein YHR040W OS=Saccharomyces cerevisiae GN=YHR040W PE=1 SV=1 [Swiss-Prot] Box C/D snoRNA protein 1 OS=Saccharomyces cerevisiae GN=BCD1 PE=1 SV=1 [Swiss-Prot] BCD1 Protein required for box C/D snoRNA accumulation [mips] Essential protein required for the accumulation of box C/D snoRNA [SGD] YHR040W, Chr VIII from 187915-189015 [yeast_orfs2] Chr VIII from 187915-189015 [yeastorf3.fasta] (P38772) Hypothetical 42.3 kDa protein in VMA10-SRB2 intergenic region [4932.FASTACCERV.txt] BCD1 SGDID:S0001082, Chr VIII from 187916-189016, Verified ORF [yeastflysequest.fasta] Bcd1p [Saccharomyces cerevisiae]gi\|731652\|sp\|P38772\|YHK0_YEAST Hypothetical protein YHR040wgi\|626609\|pir\|\|S46736 hypothetical protein YHR040w - yeast (Saccharomyces cerevisiae)gi\|488170\|gb\|AAB68905.1\| Yhr040wp [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas] (P38772) Hypothetical protein YHR040w [cerv4932.FASTAC] BCD1 SGDID:S000001082, Chr VIII from 187917-189017, Verified ORF, "Essential protein required for the accumulation of box C/D snoRNA" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Zinc-finger protein YHR040W [nr-271106-contam.fasta] Essential protein required for the accumulation of box C/D snoRNA; Bcd1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Yhr040wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Box C/D snoRNA protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BCD1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] BCD1 SGDID:S000001082, Chr VIII from 187924-189024, Genome Release 64-1-1, Verified ORF, "Essential protein required for the accumulation of box C/D snoRNA" [yeast-030211-contam.fasta] BCD1 SGDID:S000001082, Chr VIII from 187924-189024, Genome Release 64-2-1, Verified ORF, "Essential protein required for the accumulation of box C/D snoRNA" [20141208_orf_trans.fasta] TR6872\|c0_g1_i1\|g.4774 ORF TR6872\|c0_g1_i1\|g.4774 TR6872\|c0_g1_i1\|m.4774 type:complete len:367 (+) TR6872\|c0_g1_i1:35-1135(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] YHR040W SGDID:S000001082, Chr VIII from 187924-189024, Genome Release 64-1-1, Verified ORF, "Essential protein required for the accumulation of box C/D snoRNA" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	366 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA ] cytoplasm [IDA]
Biological Process:	snoRNA metabolic process [IMP]
Molecular Function:	nucleic acid binding [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVLCGVCGI KEFKYKCPRC LVQTCSLECS KKHKTRDNCS GQTHDPKEYI SSEALKQADD  60
   61 DKHERNAYVQ RDYNYLTQLK RMVHVQKMDA RMKNKRVLGP VGGHNSNFKK RRYDIDEDDR 120
  121 DSTECQRIIR RGVNCLMLPK GMQRSSQNRS KWDKTMDLFV WSVEWILCPM QEKGEKKELF 180
  181 KHVSHRIKET DFLVQGMGKN VFQKCCEFYR LAGTSSCIEG EDGSETKEER TQILQKSGLK 240
  241 FYTKTFPYNT THIMDSKKLV ELAIHEKCIG ELLKNTTVIE FPTIFVAMTE ADLPEGYEVL 300
  301 HQEPRPLEHT STLNKFIDNA REEEDAEEDS QPTEEPVQKE TQDASDSDSD SDDDYNPGLS 360
  361 MDFLTA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#03 Alpha Factor Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	BCD1	YNL165W	2	Unpublished Fields Lab Data
View Screen	BCD1	RTT106	2	Unpublished Fields Lab Data
View Screen	BCD1	HMS1	1	Unpublished Fields Lab Data
View Screen	BCD1	AHC2	1	Unpublished Fields Lab Data
View Screen	BCD1	SHE2	1	Unpublished Fields Lab Data
View Screen	BCD1	MSA2	1	Unpublished Fields Lab Data
View Screen	BCD1	SFH1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	BCD1 and SPC42	Hazbun TR, et al. (2003)
View Data	BCD1 and SPC42	Unpublished Data
View Data	BCD1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..72]	MSA	10.019989	View MSA. No confident structure predictions are available.
2	View Details	[73..366]	MSA	1.016952	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2