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Protein Overview: MAL11

General Information:
Name(s) found: MAL11 / YGR289C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; broad substrate specificity that includes maltotriose [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 616 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [TASLink to PubMed article]
    Biological Process: trehalose transport [IDALink to PubMed article]
    alpha-glucoside transport [TASLink to PubMed article]
    Molecular Function: trehalose transmembrane transporter activity [IDALink to PubMed article]
    alpha-glucoside:hydrogen symporter activity [IDALink to PubMed article][TASLink to PubMed article]
    maltose:hydrogen symporter activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNIISLVSK KKAASKNEDK NISESSRDIV NQQEVFNTED FEEGKKDSAF ELDHLEFTTN  60
   61 SAQLGDSDED NENVINEMNA TDDANEANSE EKSMTLKQAL LKYPKAALWS ILVSTTLVME 120
  121 GYDTALLSAL YALPVFQRKF GTLNGEGSYE ITSQWQIGLN MCVLCGEMIG LQITTYMVEF 180
  181 MGNRYTMITA LGLLTAYIFI LYYCKSLAMI AVGQILSAIP WGCFQSLAVT YASEVCPLAL 240
  241 RYYMTSYSNI CWLFGQIFAS GIMKNSQENL GNSDLGYKLP FALQWIWPAP LMIGIFFAPE 300
  301 SPWWLVRKDR VAEARKSLSR ILSGKGAEKD IQVDLTLKQI ELTIEKERLL ASKSGSFFNC 360
  361 FKGVNGRRTR LACLTWVAQN SSGAVLLGYS TYFFERAGMA TDKAFTFSLI QYCLGLAGTL 420
  421 CSWVISGRVG RWTILTYGLA FQMVCLFIIG GMGFGSGSSA SNGAGGLLLA LSFFYNAGIG 480
  481 AVVYCIVAEI PSAELRTKTI VLARICYNLM AVINAILTPY MLNVSDWNWG AKTGLYWGGF 540
  541 TAVTLAWVII DLPETTGRTF SEINELFNQG VPARKFASTV VDPFGKGKTQ HDSLADESIS 600
  601 QSSSIKQREL NAADKC

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) MAL11 MAL31

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] deduced N/A No confident structure predictions are available.
    2 View Details [95..299]
    [352..556]    		 PSI-BLAST 221.9691 No description for 1ja5A_ was found.
    3 View Details [300..351]
    [557..616]    		 PSI-BLAST 221.9691 No description for 1ja5A_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.52135563059944 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.52135563059944 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.6904339767429 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • binding
    		•  0.873217664940684 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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