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View Structure Prediction Details

Protein: MAL11
Organism: Saccharomyces cerevisiae
Length: 616 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAL11.

Description E-value Query
Range
Subject
Range
gi|171554 - gi|171554|gb|AAA34624.1| galactose permease
0.0 [22..607] [3..574]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
0.0 [56..606] [15..566]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [51..606] [12..567]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNIISLVSK KKAASKNEDK NISESSRDIV NQQEVFNTED FEEGKKDSAF ELDHLEFTTN  60
   61 SAQLGDSDED NENVINEMNA TDDANEANSE EKSM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [95-299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLKQALLKYP KAALWSILVS TTLVMEGYDT ALLSALYALP VFQRKFGTLN GEGSYEITSQ  60
   61 WQIGLNMCVL CGEMIGLQIT TYMVEFMGNR YTMITALGLL TAYIFILYYC KSLAMIAVGQ 120
  121 ILSAIPWGCF QSLAVTYASE VCPLALRYYM TSYSNICWLF GQIFASGIMK NSQENLGNSD 180
  181 LGYKLPFALQ WIWPAPLMIG IFFAP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [352-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKSGSFFNCF KGVNGRRTRL ACLTWVAQNS SGAVLLGYST YFFERAGMAT DKAFTFSLIQ  60
   61 YCLGLAGTLC SWVISGRVGR WTILTYGLAF QMVCLFIIGG MGFGSGSSAS NGAGGLLLAL 120
  121 SFFYNAGIGA VVYCIVAEIP SAELRTKTIV LARICYNLMA VINAILTPYM LNVSDWNWGA 180
  181 KTGLYWGGFT AVTLAWVIID LPETT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 221.9691
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 2.52135563059944 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 2.52135563059944 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 1.6904339767429 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
binding 0.873217664940684 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [300-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPWWLVRKD RVAEARKSLS RILSGKGAEK DIQVDLTLKQ IELTIEKERL LA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [557-616]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRTFSEINEL FNQGVPARKF ASTVVDPFGK GKTQHDSLAD ESISQSSSIK QRELNAADKC  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 221.9691
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle