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View Structure Prediction Details

Protein: MAL11
Organism: Saccharomyces cerevisiae
Length: 616 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAL11.

Description E-value Query
Range		 Subject
Range
gi|171554 - gi|171554|gb|AAA34624.1| galactose permease
 0.0 [22..607] [3..574]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
 0.0 [56..606] [15..566]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [51..606] [12..567]

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Predicted Domain #1
Region A:
Residues: [1-94] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNIISLVSK KKAASKNEDK NISESSRDIV NQQEVFNTED FEEGKKDSAF ELDHLEFTTN  60
   61 SAQLGDSDED NENVINEMNA TDDANEANSE EKSM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.240 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.240 a.71.1 Endoplasmic reticulum protein ERP29, C-domain

Predicted Domain #2
Region A:
Residues: [95-299] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLKQALLKYP KAALWSILVS TTLVMEGYDT ALLSALYALP VFQRKFGTLN GEGSYEITSQ  60
   61 WQIGLNMCVL CGEMIGLQIT TYMVEFMGNR YTMITALGLL TAYIFILYYC KSLAMIAVGQ 120
  121 ILSAIPWGCF QSLAVTYASE VCPLALRYYM TSYSNICWLF GQIFASGIMK NSQENLGNSD 180
  181 LGYKLPFALQ WIWPAPLMIG IFFAP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [352-556] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKSGSFFNCF KGVNGRRTRL ACLTWVAQNS SGAVLLGYST YFFERAGMAT DKAFTFSLIQ  60
   61 YCLGLAGTLC SWVISGRVGR WTILTYGLAF QMVCLFIIGG MGFGSGSSAS NGAGGLLLAL 120
  121 SFFYNAGIGA VVYCIVAEIP SAELRTKTIV LARICYNLMA VINAILTPYM LNVSDWNWGA 180
  181 KTGLYWGGFT AVTLAWVIID LPETT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 221.9691
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 2.52135563059944 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 2.52135563059944 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 1.6904339767429 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
binding 0.873217664940684 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [300-351] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPWWLVRKD RVAEARKSLS RILSGKGAEK DIQVDLTLKQ IELTIEKERL LA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [557-616] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRTFSEINEL FNQGVPARKF ASTVVDPFGK GKTQHDSLAD ESISQSSSIK QRELNAADKC  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 221.9691
Match: 1ja5A_
Description: No description for 1ja5A_ was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle