Protein Overview: DIE2

General Information:
Name(s) found:	DIE2 / YGR227W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|886920\|emb\|CAA61176.1\| ORF 525 [Saccharomyces cerevisiae] [NCBI NR] gi\|6321666\|ref\|NP_011743.1\| Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of [NCBI NR] gi\|1706435\|sp\|P50076.1\|ALG10_YEAST RecName: Full=Alpha-1,2 glucosyltransferase ALG10; AltName: Full=Alpha-2-glucosyltransferase ALG10; AltName: Full=Dolichyl-phosphoglucose-dependent glucosyltransferase ALG10; AltName: Full=Asparagine-linked glycosylation [NCBI NR] pir\|\|S57691 DIE2 protein - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1323410\|emb\|CAA97255.1\| DIE2 [Saccharomyces cerevisiae] [NCBI NR] (P50076) DIE2 protein [Swiss-Prot] Alpha-1,2 glucosyltransferase ALG10 OS=Saccharomyces cerevisiae GN=DIE2 PE=2 SV=1 [Swiss-Prot] DIE2 ITR1 expression promoting protein [mips] Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1 [SGD] DIE2, Chr VII from 947412-948989 [yeast_orfs2] Chr VII from 947412-948989 [yeastorf3.fasta] Chr VII from 947419-948996 [yeastorf4.fasta] DIE2 SGDID:S0003459, Chr VII from 947420-948997, Verified ORF [yeastflysequest.fasta] DIE2 SGDID:S0003459, Chr VII from 947422-948999, Verified ORF [10112005cervSGD.fasta] Die2p [Saccharomyces cerevisiae]gi\|886920\|emb\|CAA61176.1\| ORF 525 [Saccharomyces cerevisiae]gi\|1323410\|emb\|CAA97255.1\| DIE2 [Saccharomyces cerevisiae]gi\|1362331\|pir\|\|S57691 DIE2 protein - yeast (Saccharomyces cerevisiae)gi\|1706435\|sp\|P50076\|DIE2_YEAST [nrdb_11152004_Chlamydomonas] DIE2 SGDID:S000003459, Chr VII from 947423-949000, Verified ORF, "Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in the dolichol pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycos [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] DIE2 SGDID:S000003459, Chr VII from 947423-949000, Verified ORF, "Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glyco [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] ORF 525 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] DIE2 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in the dolichol pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1; Die2p [Sacchar [nr-271106-contam.fasta] Alpha-1,2 glucosyltransferase ALG10 (Alpha-2-glucosyltransferase ALG10) (Dolichyl-phosphoglucose-dependent glucosyltransferase ALG10) (Asparagine-linked glycosylation protein 10) [nr-271106-contam.fasta] DIE2 SGDID:S000003459, Chr VII from 947423-949000, Verified ORF, "Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1" [yeast-bovrabprots.fasta] DIE2 SGDID:S000003459, Chr VII from 947423-949000, Verified ORF, "Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in the dolichol pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1" [yeast-contam_custom.fasta] [chemostatdb.fasta]
Organism:	Saccharomyces cerevisiae
Length:	525 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IMP]
Biological Process:	protein amino acid N-linked glycosylation [IMP] dolichol-linked oligosaccharide biosynthetic process [TAS]
Molecular Function:	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAKKNTGEA NNDVLEEEAA IQLIAPGIAR NLTQEVITGI FCNVVIYPLL LIYFVLTFRY  60
   61 MTTNIVPYEF IDEKFHVGQT LTYLKGKWTQ WDPKITTPPG IYILGLINYY CIKPIFKSWS 120
  121 TLTILRLVNL LGGIIVFPIL VLRPIFLFNA LGFWPVSLMS FPLMTTYYYL FYTDVWSTIL 180
  181 ILQSLSCVLT LPFGPVKSIW LSAFFAGVSC LFRQTNIIWT GFIMILAVER PAILQKQFNT 240
  241 HTFNNYLKLF IHAIDDFSNL VLPYMKNFVL FFIYLIWNRS ITLGDKSSHS AGLHIVQIFY 300
  301 CFTFITVFSL PIWISRNFMK LYKLRIKRKP VQTFFEFIGI MLIIRYFTKV HPFLLADNRH 360
  361 YTFYLFRRLI GNKSRLIKYF FMTPIYHFST FAYLEVMRPN QLTFHPITPL PIKEPVHLPI 420
  421 QLTHVSWTAL ITCTMVTIVP SPLFEPRYYI LPYFFWRIFI TCSCEPLIKD LKPAKEGENP 480
  481 ITISSTKRLF MEFLWFMLFN VVTLVIFSKV SFPWTTEPYL QRIIW

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		ALG13 ALG8 DIE2 STT3

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..412]	MSA	1.010932	View MSA. No confident structure predictions are available.
2	View Details	[413..525]	deduced	N/A	No confident structure predictions are available.

Protein Overview: DIE2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: