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Protein Overview: TOS2

General Information:
Name(s) found: TOS2 / YGR221C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein involved in localization of Cdc24p to the site of bud growth; may act as a membrane anchor; localizes to the bud neck and bud tip; potentially phosphorylated by Cdc28p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 622 amino acids

    Gene Ontology:
    Cellular Component: cellular bud tip [IDALink to PubMed articleLink to PubMed article]
    cellular bud neck [IDALink to PubMed articleLink to PubMed article]
    Biological Process: budding cell bud growth [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSHYRYKEN SCQKREAIPD KSRVSLTFLQ KRTDSSNVTV AVAVAVPIGA IIIVLSVVLI  60
   61 VVYRRCKKNL LCRILTQILR AIYTIYRRWI TSMNSANSDS NATEKRFIYG GYDDFLQPSI 120
  121 ENSQSFKDYV RRINEHAPSA YNIASLASQN NSKLSVPSKH IDLSNKISFE SLENSELIVS 180
  181 PQHSNTGQDC DQRCDSTSNP DVNEKSSHNN DNRLKSNYTS RSGLEPQCSR EEEENIDRIR 240
  241 SIYNIYFEKS NSTIRSSVTS SIRRDSKLNI ATRKSVNMSS QDNPNDTTLI EQSHFGSTTV 300
  301 QEIDSSSSAN EEYEDATDYL QVPAPQENKN IASSVYSEVA TREKVIPESS LSLTFPPPNG 360
  361 LSTRITSSIY SDTVAKDHIH SAKAPVRALS EGSGQSNLTS AQQYSTYFID HCNQSNDDNY 420
  421 YYNYPLPLEH PQNYENIGDL PTPTQFIYST SSHSLTSFKG RPKPPKTLKH VPTARLNGTA 480
  481 LNPMDHPEMF YSSPTKIPST SLTKQFCTPL PYQLRQSVVM TNPSELSMKP RYKPAGSLRN 540
  541 LIKAQYLPGN SSTTTSSSLS QPPSTLSNAI NFRVSGLLDD TDILQPPSVG EILPFKASTE 600
  601 DLRKQLGTSH NYEITPYENV HV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC24 TOS2 2 Drees BL, et al. (2001)
    View Screen CIA1 TOS2 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TOS2 Sundin BA, et al. (2004)
    View Data TOS2 Sundin BA, et al. (2004)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..179] deduced N/A No confident structure predictions are available.
    2 View Details [180..622] MSA 1.003872 View MSA. No confident structure predictions are available.
    3 View Details [344..412] deduced N/A No confident structure predictions are available.
    4 View Details [413..622] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle