Protein Overview: TAD1

General Information:
Name(s) found:	TAD1 / YGL243W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|793869\|emb\|CAA89012.1\| HRA400 [Saccharomyces cerevisiae] [NCBI NR] gi\|6321194\|ref\|NP_011271.1\| tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala; Tad1p [Saccharomyces cerevisiae] [NCBI NR] gi\|3250918\|emb\|CAA07438.1\| Tad1p; scADAT1 [Saccharomyces cerevisiae] [NCBI NR] gi\|1723979\|sp\|P53065.1\|TAD1_YEAST RecName: Full=tRNA-specific adenosine deaminase 1; AltName: Full=tRNA-specific adenosine-37 deaminase [NCBI NR] gi\|1589349\|prf\|\|2210407D HRA400 gene [NCBI NR] gi\|1322911\|emb\|CAA96962.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S53937 hypothetical protein YGL243w - yeast (Saccharomyces cerevisiae) [NCBI NR] tRNA-specific adenosine deaminase 1 OS=Saccharomyces cerevisiae GN=TAD1 PE=1 SV=1 [Swiss-Prot] TAD1 tRNA-specific adenosine deaminase 1 [mips] tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala [SGD] TAD1, Chr VII from 43307-44509 [yeast_orfs2] Chr VII from 43307-44509 [yeastorf3.fasta] (P53065) tRNA-specific adenosine deaminase 1 (EC 3.5.4.-) (tRNA-specific adenosine-37 deaminase) [4932.FASTACCERV.txt] TAD1 SGDID:S0003212, Chr VII from 43307-44509, Verified ORF [yeastflysequest.fasta] Tad1p [Saccharomyces cerevisiae]gi\|1322911\|emb\|CAA96962.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|793869\|emb\|CAA89012.1\| HRA400 [Saccharomyces cerevisiae]gi\|3250918\|emb\|CAA07438.1\| Tad1p; scADAT1 [Saccharomyces cerevisiae]gi\|1077166\|pir\| [nrdb_11152004_Chlamydomonas] TAD1 SGDID:S000003212, Chr VII from 43307-44509, Verified ORF, "tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Tad1p; scADAT1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] HRA400 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala; Tad1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] tRNA-specific adenosine deaminase 1 (tRNA-specific adenosine-37 deaminase) [nr-271106-contam.fasta] HRA400 gene [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] tRNA-specific adenosine deaminase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TAD1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] TAD1 SGDID:S000003212, Chr VII from 43307-44509, Genome Release 64-1-1, Verified ORF, "tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala" [yeast-030211-contam.fasta] TAD1 SGDID:S000003212, Chr VII from 43307-44509, Genome Release 64-2-1, Verified ORF, "tRNA-specific adenosine deaminase; deaminates adenosine-37 to inosine in tRNA-Ala" [20141208_orf_trans.fasta] YGL243W SGDID:S000003212, Chr VII from 43307-44509, Genome Release 64-1-1, Verified ORF, "tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	400 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	tRNA modification [IDA]
Molecular Function:	tRNA-specific adenosine deaminase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSCQGTRPC IVNLLTMPSE DKLGEEISTR VINEYSKLKS ACRPIIRPSG IREWTILAGV  60
   61 AAINRDGGAN KIEILSIATG VKALPDSELQ RSEGKILHDC HAEILALRGA NTVLLNRIQN 120
  121 YNPSSGDKFI QHNDEIPARF NLKENWELAL YISRLPCGDA SMSFLNDNCK NDDFIKIEDS 180
  181 DEFQYVDRSV KTILRGRLNF NRRNVVRTKP GRYDSNITLS KSCSDKLLMK QRSSVLNCLN 240
  241 YELFEKPVFL KYIVIPNLED ETKHHLEQSF HTRLPNLDNE IKFLNCLKPF YDDKLDEEDV 300
  301 PGLMCSVKLF MDDFSTEEAI LNGVRNGFYT KSSKPLRKHC QSQVSRFAQW ELFKKIRPEY 360
  361 EGISYLEFKS RQKKRSQLII AIKNILSPDG WIPTRTDDVK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#03 Alpha Factor Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	MSN5	TAD1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..69]	deduced	N/A	No confident structure predictions are available.
2	View Details	[70..400]	Pfam	4.677781	Adenosine-deaminase (editase) domain No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2