Protein Overview: SCS3

General Information:
Name(s) found:	SCS3 / YGL126W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6321312\|ref\|NP_011389.1\| Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol; Scs3p [Sa [NCBI NR] gi\|1711345\|sp\|P53012.1\|SCS3_YEAST RecName: Full=FIT family protein SCS3 [NCBI NR] gi\|1407585\|dbj\|BAA04742.1\| SCS3 [Saccharomyces cerevisiae] [NCBI NR] gi\|1322689\|emb\|CAA96835.1\| SCS3 [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S53293 SCS3 protein - yeast (Saccharomyces cerevisiae) [NCBI NR] FIT family protein SCS3 OS=Saccharomyces cerevisiae GN=SCS3 PE=1 SV=1 [Swiss-Prot] Protein FIT2 homolog B OS=Saccharomyces cerevisiae GN=SCS3 PE=1 SV=1 [Swiss-Prot] SCS3 Inositol phospholipid synthesis protein [mips] Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol [SGD] SCS3, Chr VII from 271001-272143 [yeast_orfs2] Chr VII from 271001-272143 [yeastorf3.fasta] (P53012) SCS3 protein [4932.FASTACCERV.txt] SCS3 SGDID:S0003094, Chr VII from 271001-272143, Verified ORF [yeastflysequest.fasta] SCS3 SGDID:S0003094, Chr VII from 271003-272145, Verified ORF [10112005cervSGD.fasta] Protein required for inositol prototrophy [Saccharomyces cerevisiae]gi\|1322689\|emb\|CAA96835.1\| SCS3 [Saccharomyces cerevisiae]gi\|1078355\|pir\|\|S53293 SCS3 protein - yeast (Saccharomyces cerevisiae)gi\|1407585\|dbj\|BAA04742.1\| SCS3 [Saccharomyces cerevisia [nrdb_11152004_Chlamydomonas] SCS3 SGDID:S000003094, Chr VII from 271003-272145, Verified ORF, "Protein required for inositol prototrophy, appears to be involved in the synthesis of inositol phospholipids from inositol but not in the control of inositol synthesis" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] SCS3 SGDID:S000003094, Chr VII from 271003-272145, Verified ORF, "Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] Protein required for inositol prototrophy, appears to be involved in the synthesis of inositol phospholipids from inositol but not in the control of inositol synthesis; Scs3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] SCS3 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein SCS3 [nr-271106-contam.fasta] SCS3 SGDID:S000003094, Chr VII from 271003-272145, Verified ORF, "Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol" [yeast-bovrabprots.fasta] [chemostatdb.fasta] FIT family protein SCS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SCS3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SCS3 SGDID:S000003094, Chr VII from 270997-272139, Genome Release 64-1-1, Verified ORF, "Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol" [yeast-030211-contam.fasta] SCS3 SGDID:S000003094, Chr VII from 270997-272139, Genome Release 64-2-1, Verified ORF, "Protein required for inositol prototrophy; required for normal ER membrane biosynthesis; ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis and homologous to human FIT2; disputed role in the synthesis of inositol phospholipids from inositol" [20141208_orf_trans.fasta] YGL126W SGDID:S000003094, Chr VII from 270997-272139, Genome Release 64-1-1, Verified ORF, "Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	380 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA]
Biological Process:	phospholipid metabolic process [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKWFNAIH LLVCPLTVLV GYLMNAYGYG AALQATLNKD GLVNAMLVKK GWFWTSLVGW  60
   61 WCIIRYRAVP GATGRDRRHI VQSFKRYAIL TVWWYVFTQG IWFGVGPIMD LVFVYTGGHC 120
  121 HYDVFDDAGH VNEDFQGSVT RTNRALALIH NVLTLHGHHQ EHRQQQLWDR SIGSIQGALQ 180
  181 ATQPKTPKNV TASAAAAINT FIHDQMHRWQ GPLTTSAQCR RFGGHWAGGH DPSGHVFLAT 240
  241 LMCMFLLGEL RVFGRRALAH LYAQKWQLVR LVTRLFDTGP LWTWRRCGGG SMTCGARLWR 300
  301 AIVEPPVTCA AALLRLTRCI ACDHPVIILL TLLVTWLWQL LLTAVASRFH TVREHMSGLL 360
  361 AAYIVTGLVY ARDAAALRPV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	SCS3	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..127]	MSA	9.014995	View MSA. Confident ab initio structure predictions are available.
2	View Details	[128..230]	deduced	N/A	No confident structure predictions are available.
3	View Details	[231..380]	MSA	1.00693	View MSA. No confident structure predictions are available.

Protein Overview: SCS3

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: