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Protein Overview: FCY21

General Information:
Name(s) found: FCY21 / YER060W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 528 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISSLink to PubMed article]
    Biological Process: biological_process [ND]
    AMP metabolic process [ISSLink to PubMed article]
    Molecular Function: nucleobase transmembrane transporter activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQTHEMSLN GTQYLKYELK DLESRAHDAK TPSTNEFYDD VESHGTEELV EAKLSFLNRI  60
   61 AAGLSAETKG IEPITEDEKT DDSILNAASM WFSANMVLPA YAIGALGPMV FDLNFGQSVF 120
  121 VIIFFNLLGL VSVAFFSVFG AELGLRQMIL SRYLVGNIAA RIFSFINFIA CIGWGIVNTV 180
  181 ASSQVLNMVN PGHQCPLWAG CIVIIGATVI VTFFGYGVIH AYEKWAWVPN FAVFLVIIAR 240
  241 LARSKKFVLG EWTSGPTTAG NVLSFGSTVY GFAAGWTTYA ADYTVYMPRK TNKYKIFFSL 300
  301 VVGLATPLYF TMILGAAVAM AAIGDPAWKT YYDENSIGGL TFAVLVPNSV HGFGQFCCVL 360
  361 LSLSTIANNV PNMYTIALSV QATWEPLAKV PRVIWTLLGN AAALGIAIPA CYYFSTFMNY 420
  421 FMDSIGYYLA IYIAIACSEH FIYRRSFSAY NVDDWDSWER LPIGIAGTAA LIVGAFGVAL 480
  481 GMCQTYWVGE ISRLIGDYGG DIGFELGLSW AFIVYNIARP FELKYFGR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) FCY21 MTG1 SPB4 YBL071C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [70..528] Pfam 155.823909 Permease for cytosine/purines, uracil, thiamine, allantoin No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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