Protein Overview: CHO1

General Information:
Name(s) found:	CHO1 / YER026C [SGD]
Description(s) found: Found 32 descriptions. SHOW ALL	Phosphatidylserine synthase, functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline [SGD]
Organism:	Saccharomyces cerevisiae
Length:	276 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [TAS]
Biological Process:	phosphatidylserine biosynthetic process [IDA][IMP][TAS]
Molecular Function:	CDP-diacylglycerol-serine O-phosphatidyltransferase activity [IDA][IMP][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVESDEDFAP QEFPHTDTDV IVNEHRDEND GYASDEVGGT LSRRASSIFS INTTPLAPPN  60
   61 ATDIQKFTSD EHHFSMMRNL HMADYITMLN GFSGFYSIVS CLRFTLTGKP HYVQRAHFFI 120
  121 LLGMCFDFLD GRVARLRNRS SLMGQELDSL ADLVSFGVAP AAIAFAIGFQ TTFDVMILSF 180
  181 FVLCGLARLA RFNVTVAQLP KDSSTGKSKY FEGLPMPTTL ALVLGMAYCV RKGLIFDNIP 240
  241 FGIFREDQIL EFHPIILVFF IHGCGMISKS LKIPKP

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		CHO1 GPI11

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	BRR2	CHO1	1	Unpublished Fields Lab Data
View Screen	ROM1	CHO1	1	Unpublished Fields Lab Data
View Screen	IRE1	CHO1	1	Unpublished Fields Lab Data
View Screen	SXM1	CHO1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..109]	deduced	N/A	No confident structure predictions are available.
2	View Details	[110..276]	Pfam	31.136677	CDP-alcohol phosphatidyltransferase No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2