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Protein Overview: YAT2

General Information:
Name(s) found: YAT2 / YER024W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Carnitine acetyltransferase; has similarity to Yat1p, which is a carnitine acetyltransferase associated with the mitochondrial outer membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 923 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: alcohol metabolic process [IGILink to PubMed article][IMPLink to PubMed article]
    carnitine metabolic process [IMPLink to PubMed article]
    Molecular Function: carnitine O-acetyltransferase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGSTIVSS DKSGRTFKHE EELPKLPLPK LCDTLQRLKE SLEPLYYADG YYQHPLDPEQ  60
   61 IEKLSSIIRD FEENPVSEKL QSKLQSYHDT RDCYLDELHL DINNQTSTRE IQDDVLPRNP 120
  121 FLVLADDALP NITQADRSAV LVHSAARFIS ALKQDLLPPD INATNGKPLS MAPFLNLFGT 180
  181 TRSPVFQRGE VENFDLNKPY TASDLEDPDY SSDEDDNDEP TQKDFDDRKR KHEEDIFTGN 240
  241 GITIKRHPDS KHILIISRGQ YYTLEVLDST NKIIYTAAEL TTIFNHIIKD SSGIEKSTAL 300
  301 GSLTSHSFRN WKYARKRLQK RYPNELHRID SALFVLVLDE SQEETTNDGD DTADISQMFN 360
  361 RTITERDKKC TSANCKRVFY GTSIINSKGH QVGSCVSRWY DKLQLVVTAD AKATVIWDSF 420
  421 TCDGSVVLRF TSEIYTESVL RLARDVNAGD PQFSLWPNVT QMDPETKKLM TATISADGGG 480
  481 PSEIDPKLVV NKIDWSFSNI LNTHVHLSET KLADLISKYD IVRASIPLGR RSAQRLGVKP 540
  541 DSMVQVALQI AHYALYGRMV FGLEPVSTRG FKNSRSSFIN IQSQALLELC QLFISSSIDG 600
  601 TDKLDKFIQT CETHNNMVKH AKSGVGYEKH FNALKYLFKF HDHFGIHLSG DESSAAKDLF 660
  661 ENPLVLPFSQ PELIVANCGN AATTTFGITP AVPHGFGIGY IIKDDQVDLT VTSQFRQGDR 720
  721 LMFMLSWVLG EIRSYWRMSR GTSHNKTGVK ISPVVDKLYE MDNAVNNPPK RNGHTVNGSR 780
  781 KTSSSSQVNL NRYGGFFDLE GHIDSRNISK TPSMKNLQKT FNGLTMSADN DHSSSAVSVP 840
  841 TEKEKLNTGH EILQIQPREV ASNGLEADDE TDIEIVAGNA DGTSSSASSA TSLNSKKRNV 900
  901 INSRFDIDFD RSRVGRKVAT LDQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YAT2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..780] Pfam 245.455932 Choline/Carnitine o-acyltransferase No confident structure predictions are available.
    2 View Details [781..923] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • carnitine O-acyltransferase activity
    		•  7.54616819269984 bayes_pls_golite062009
  • carnitine O-acetyltransferase activity
    		•  7.38318207912192 bayes_pls_golite062009
  • choline O-acetyltransferase activity
    		•  6.09272417016149 bayes_pls_golite062009
  • octanoyltransferase activity
    		•  4.52268776339565 bayes_pls_golite062009
  • O-octanoyltransferase activity
    		•  4.52268776339565 bayes_pls_golite062009
  • carnitine O-octanoyltransferase activity
    		•  4.52268776339565 bayes_pls_golite062009
  • carnitine O-palmitoyltransferase activity
    		•  3.83467723502092 bayes_pls_golite062009
  • O-palmitoyltransferase activity
    		•  3.83467723502092 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.7327637835604 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  3.7101056995294 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.08588280042054 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.027770031317 bayes_pls_golite062009
  • S-acyltransferase activity
    		•  2.74258684113582 bayes_pls_golite062009
  • O-acetyltransferase activity
    		•  2.37098434941789 bayes_pls_golite062009
  • dihydrolipoamide S-acyltransferase activity
    		•  2.20915191604487 bayes_pls_golite062009
  • dihydrolipoyllysine-residue acetyltransferase activity
    		•  2.0783127648124 bayes_pls_golite062009
  • S-acetyltransferase activity
    		•  2.04797137596259 bayes_pls_golite062009
  • transferase activity
    		•  1.78692523095641 bayes_pls_golite062009
  • choline binding
    		•  1.59193088660278 bayes_pls_golite062009
  • catalytic activity
    		•  1.51562638409295 bayes_pls_golite062009
  • succinyltransferase activity
    		•  1.48650517081097 bayes_pls_golite062009
  • acetyltransferase activity
    		•  1.12787027896966 bayes_pls_golite062009
  • S-succinyltransferase activity
    		•  1.03771162623809 bayes_pls_golite062009
  • dihydrolipoyllysine-residue succinyltransferase activity
    		•  1.03771162623809 bayes_pls_golite062009
  • binding
    		•  0.999555841397607 bayes_pls_golite062009
  • palmitoyltransferase activity
    		•  0.607756896737891 bayes_pls_golite062009
  • protein binding
    		•  0.104367069798378 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle