Protein Overview: TIR1

General Information:
Name(s) found:	TIR1 / YER011W [SGD]
Description(s) found: Found 24 descriptions. SHOW ALL	Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking [SGD]
Organism:	Saccharomyces cerevisiae
Length:	254 amino acids
Gene Ontology:
Cellular Component:	fungal-type cell wall [IDA ]
Biological Process:	response to stress [ISS]
Molecular Function:	structural constituent of cell wall [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYTKIALFA AIAALASAQT QDQINELNVI LNDVKSHLQE YISLASDSSS GFSLSSMPAG  60
   61 VLDIGMALAS ATDDSYTTLY SEVDFAGVSK MLTMVPWYSS RLEPALKSLN GDASSSAAPS 120
  121 SSAAPTSSAA PSSSAAPTSS AASSSSEAKS SSAAPSSSEA KSSSAAPSSS EAKSSSAAPS 180
  181 SSEAKSSSAA PSSTEAKITS AAPSSTGAKT SAISQITDGQ IQATKAVSEQ TENGAAKAFV 240
  241 GMGAGVVAAA AMLL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#04 Alpha Factor Prep2	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CTF13	TIR1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	TIR1	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..254]	ORFEUS	12.14	Fibrinogen

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2