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Protein Overview: TIR1

General Information:
Name(s) found: TIR1 / YER011W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 254 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed articleLink to PubMed article]
    Biological Process: response to stress [ISSLink to PubMed article]
    Molecular Function: structural constituent of cell wall [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYTKIALFA AIAALASAQT QDQINELNVI LNDVKSHLQE YISLASDSSS GFSLSSMPAG  60
   61 VLDIGMALAS ATDDSYTTLY SEVDFAGVSK MLTMVPWYSS RLEPALKSLN GDASSSAAPS 120
  121 SSAAPTSSAA PSSSAAPTSS AASSSSEAKS SSAAPSSSEA KSSSAAPSSS EAKSSSAAPS 180
  181 SSEAKSSSAA PSSTEAKITS AAPSSTGAKT SAISQITDGQ IQATKAVSEQ TENGAAKAFV 240
  241 GMGAGVVAAA AMLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #04 Alpha Factor Prep2 Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TIR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..254] ORFEUS 12.14 Fibrinogen


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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