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Protein Overview: YDR532C

General Information:
Name(s) found: YDR532C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Subunit of a kinetochore-microtubule binding complex with Spc105p that bridges centromeric heterochromatin and kinetochore MAPs and motors, and is also required for sister chromatid bi-orientation and kinetochore binding of SAC components [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 385 amino acids

    Gene Ontology:
    Cellular Component: spindle pole body [IDALink to PubMed article]
    Biological Process: telomere maintenance [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTGSASIKD YETVLTDIED SIAVSSEEVL NNQELRLKNT LHEITSSILA INEENKFVNP  60
   61 LRNDESLDVE GKEVFVNPKI LSAKIKEFNK LMELLKLTYL EQETLDYFFR FTLSSTKPLQ 120
  121 LDSEKDPQFV KLNERVNDLK EEISNVQESK IEQIKAEIQE TGHNFAERQD LINELYLEAT 180
  181 GDIENCWDSL NELKNLTNKE DKNMMGEKDT ILNSSDSDDF VEETYTNWQK LLFLQKQNQR 240
  241 LTKELKEMHE VKNQIIRKGE QSKKEDSGHL MANESELCQS INLLTKFWEK HFLLKGSKTT 300
  301 ILNFEIFTQL GKVQFEIKDM QYIIAISLSD LKRPMIKDIT ILQKAGGNIV TDIEASSKFN 360
  361 NKYRNNTKVQ IFEVMDDIIS ELTNE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) SPC105 YDR532C
    View Details Qiu et al. (2008) TID3 YDR532C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen IRE1 YDR532C 2 Uetz P, et al. (2000)
    View Screen ESF2 YDR532C 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YDR532C Huh WK, et al. (2003)
    View Data YDR532C and SPC42 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..131] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [132..277]
    [324..385]    		 ORFEUS 7.44 Hemolysin E (HlyE, ClyA, SheA)
    3 View Details [278..323] ORFEUS 7.44 Hemolysin E (HlyE, ClyA, SheA)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle