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Protein Overview: DFM1

General Information:
Name(s) found: DFM1 / YDR411C [SGD]
Description(s) found:
Found 29 descriptions.
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  • ER localized derlin-like family member involved in ER stress and homeostasis; not involved in ERAD or substrate retrotranslocation; interacts with CDC48; contains four transmembrane domains and two SHP boxes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 341 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed articleLink to PubMed article]
    Biological Process: endoplasmic reticulum unfolded protein response [IGILink to PubMed article][IMPLink to PubMed article]
    [NOT]ER-associated protein catabolic process [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGPRNVRTL HGNGGRNNDV MGPKEFWLNI PPITRTLFTL AIVMTIVGRL NLINPWYFIY  60
   61 VWNLTFKKVQ IWRLLTSCVM LSSRAMPALM ELYSIYDRSS QLERGHFGPG LSNRRGPMVT 120
  121 VDYAYYLCFC ILAITTATTI IYGSYYPVVL TSGFISCITY TWSIDNANVQ IMFYGLIPVW 180
  181 GKYFPLIQLF ISFVFNEGDF VISLIGFTTG YLYTCLDTHT LGPIWGMISR KADPTYGISP 240
  241 NGKFSTPWWF TSLYARITGA HNETATFNNN FANVPSSQRE TRTFSGRGQR LGTAPATLSQ 300
  301 TSGTDSGRAS GSQLRSGPSN LNQFQGRGQR VGQTNSPSDS Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YIF1 DFM1 2 Unpublished Fields Lab Data
    View Screen PEX22 DFM1 2 Unpublished Fields Lab Data
    View Screen HMT1 DFM1 1 Unpublished Fields Lab Data
    View Screen ERG27 DFM1 1 Unpublished Fields Lab Data
    View Screen UBC12 DFM1 1 Unpublished Fields Lab Data
    View Screen HOF1 DFM1 1 Unpublished Fields Lab Data
    View Screen RRB1 DFM1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data DFM1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..267] MSA 107.161997 View MSA. No confident structure predictions are available.
    2 View Details [268..341] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.27938828612061 bayes_pls_golite062009
  • protein binding
    		•  1.72968950672856 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.172760623576326 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.156922202244152 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.0437862640556833 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle