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Protein Overview: INM2

General Information:
Name(s) found: INM2 / YDR287W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesium ions and is inhibited by lithium and sodium ions; inm1 inm2 double mutant lacks inositol auxotrophy [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 292 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: inositol phosphate dephosphorylation [IDALink to PubMed article]
    Molecular Function: inositol-1(or 4)-monophosphatase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLTRQVLEE VENTFIELLR SKIGPLVKSH AGTNFCSYDD KANGVDLVTA LDKQIESIIK  60
   61 ENLTAKYPSF KFIGEETYVK GVTKITNGPT FIVDPIDGTT NFIHGYPYSC TSLGLAEMGK 120
  121 PVVGVVFNPH LNQLFHASKG NGAFLNDQEI KVSKRPLILQ KSLIALEGGS ERTEGSQGNF 180
  181 DKKMNTYKNL LSESGAFVHG FRSAGSAAMN ICYVASGMLD AYWEGGCWAW DVCAGWCILE 240
  241 EAGGIMVGGN CGEWNIPLDR RCYLAIRGGC ESMEQKRFAE SFWPHVAGEL EY

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) INM2 YNL035C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] PSI-BLAST 469.68867 Inositol monophosphatase
    2 View Details [149..292] PSI-BLAST 469.68867 Inositol monophosphatase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle