YRC Public Data Repository - Protein Structure Prediction

Protein:	INM2
Organism:	Saccharomyces cerevisiae
Length:	292 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INM2.

Description	E-value	Query Range	Subject Range
INM2 - Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesiu... INM2_YEAST - Inositol monophosphatase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=INM2 PE=1 SV=...	1.0E-76	[1..292]	[1..292]
IMPA1_RAT - Inositol monophosphatase 1 OS=Rattus norvegicus GN=Impa1 PE=1 SV=2	6.0E-72	[6..284]	[3..273]
IMPA1 - inositol(myo)-1(or 4)-monophosphatase 1	7.0E-72	[6..284]	[3..273]
gi\|74137533, gi\|... - gi\|74227685\|dbj\|BAE35691.1\| unnamed protein product [Mus musculus], gi\|74220541\|dbj\|BAE31486.1\| unna...	5.0E-71	[6..284]	[3..273]
IMPA1_BOVIN - Inositol monophosphatase 1 OS=Bos taurus GN=IMPA1 PE=1 SV=1	3.0E-70	[6..284]	[3..273]
IMPA1_PIG - Inositol monophosphatase 1 OS=Sus scrofa GN=IMPA1 PE=2 SV=1	4.0E-70	[6..284]	[3..273]
SUHB_ECO57 - Inositol-1-monophosphatase OS=Escherichia coli O157:H7 GN=suhB PE=3 SV=1 EG10983 - inositol monophosphatase / Inositol-1-monophosphatase; mutation suppresses TS growth phenotype of rp... EG10983 - inositol monophosphatase / Inositol-1-monophosphatase; mutation suppresses TS growth phenotype of rp... SUHB_ECOL6 - Inositol-1-monophosphatase OS=Escherichia coli O6 GN=suhB PE=3 SV=1 gi\|117624761, gi... - gi\|117624761\|ref\|YP_853674.1\| inositol monophosphatase [Escherichia coli APEC O1], gi\|115513885\|gb\|A... gi\|124499821, gi... - gi\|124529514\|ref\|ZP_01700484.1\| Inositol-phosphate phosphatase [Escherichia coli B], gi\|124499821\|gb... SUHB_ECOL6 - Inositol-1-monophosphatase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=suhB PE... gi\|170082143, gi... - gi\|170082143\|ref\|YP_001731463.1\| inositol monophosphatase [Escherichia coli str. K-12 substr. DH10B]... gi\|170019184, gi... - gi\|170019184\|ref\|YP_001724138.1\| inositol monophosphatase [Escherichia coli ATCC 8739], gi\|169754112... gi\|195936680 - gi\|195936680\|ref\|ZP_03082062.1\| inositol monophosphatase [Escherichia coli O157:H7 str. EC4024] gi\|170682874, gi... - gi\|170682874\|ref\|YP_001744722.1\| inositol-1-monophosphatase [Escherichia coli SMS-3-5], gi\|170520592... gi\|208813681, gi... - gi\|208813681\|ref\|ZP_03255010.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4045], g... gi\|208808370, gi... - gi\|208808370\|ref\|ZP_03250707.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4206], g... gi\|209157326, gi... - gi\|209395926\|ref\|YP_002272008.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4115], ... gi\|208741036, gi... - gi\|208820913\|ref\|ZP_03261233.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4042], g... gi\|189355312, gi... - gi\|189355312\|gb\|EDU73731.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4401], gi\|16... gi\|168748401, gi... - gi\|188017128\|gb\|EDU55250.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4113], gi\|16... gi\|189362295, gi... - gi\|189362295\|gb\|EDU80714.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4486], gi\|16... gi\|189368450, gi... - gi\|189368450\|gb\|EDU86866.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4501], gi\|16... gi\|168778506, gi... - gi\|189003173\|gb\|EDU72159.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4076], gi\|16... gi\|168773545, gi... - gi\|187770647\|gb\|EDU34491.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4196], gi\|16... gi\|189378556, gi... - gi\|189378556\|gb\|EDU96972.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC508], gi\|168... gi\|189372355, gi... - gi\|189372355\|gb\|EDU90771.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC869], gi\|168... gi\|75515872, gi\|... - gi\|75515872\|ref\|ZP_00738007.1\| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of ... gi\|218706036, gi... - gi\|218706036\|ref\|YP_002413555.1\| inositol monophosphatase [Escherichia coli UMN026], gi\|218433133\|em... gi\|81246393, gi\|... - gi\|82544982\|ref\|YP_408929.1\| inositol monophosphatase [Shigella boydii Sb227], gi\|81246393\|gb\|ABB671... gi\|218701043, gi... - gi\|218701043\|ref\|YP_002408672.1\| inositol monophosphatase [Escherichia coli IAI39], gi\|218371029\|emb... gi\|237705044, gi... - gi\|237705044\|ref\|ZP_04535525.1\| inositol-1-monophosphatase [Escherichia sp. 3_2_53FAA], gi\|226901410... gi\|194419648, gi... - gi\|83570753\|ref\|ZP_00922196.1\| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of ... gi\|215487883, gi... - gi\|215487883\|ref\|YP_002330314.1\| inositol monophosphatase [Escherichia coli O127:H6 str. E2348/69], ... gi\|238901698, gi... - gi\|238901698\|ref\|YP_002927494.1\| inositol monophosphatase [Escherichia coli BW2952], gi\|238861512\|gb... gi\|194423451, gi... - gi\|83586817\|ref\|ZP_00925448.1\| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of ... gi\|89109339, gi\|... - gi\|89109339\|ref\|AP_003119.1\| inositol monophosphatase [Escherichia coli str. K-12 substr. W3110], gi... gi\|209913270, gi... - gi\|209920011\|ref\|YP_002294095.1\| inositol monophosphatase [Escherichia coli SE11], gi\|209913270\|dbj\|... gi\|242378133, gi... - gi\|251785860\|ref\|YP_003000164.1\| hypothetical protein B21_02389 [Escherichia coli BL21], gi\|24237813... gi\|157155322, gi... - gi\|75187285\|ref\|ZP_00700552.1\| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of ... gi\|91211860, gi\|... - gi\|91211860\|ref\|YP_541846.1\| inositol monophosphatase [Escherichia coli UTI89], gi\|91073434\|gb\|ABE08... gi\|218355571, gi... - gi\|218548030\|ref\|YP_002381821.1\| inositol monophosphatase [Escherichia fergusonii ATCC 35469], gi\|21... gi\|254289268, gi... - gi\|254289268\|ref\|YP_003055016.1\| inositol monophosphatase [Escherichia coli BL21(DE3)], gi\|253978575... gi\|157162009, gi... - gi\|75196550\|ref\|ZP_00706620.1\| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of ... gi\|13362870, gi\|... - gi\|15832653\|ref\|NP_311426.1\| inositol monophosphatase [Escherichia coli O157:H7 str. Sakai], gi\|1336... gi\|217319850, gi... - gi\|217327483\|ref\|ZP_03443566.1\| inositol-1-monophosphatase [Escherichia coli O157:H7 str. TW14588], ... gi\|254162507, gi... - gi\|254162507\|ref\|YP_003045615.1\| inositol monophosphatase [Escherichia coli B str. REL606], gi\|25397... gi\|194414698, gi... - gi\|75211499\|ref\|ZP_00711589.1\| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of ... gi\|218366228, gi... - gi\|218559459\|ref\|YP_002392372.1\| inositol monophosphatase [Escherichia coli S88], gi\|218366228\|emb\|C... gi\|254794483, gi... - gi\|254794483\|ref\|YP_003079320.1\| inositol monophosphatase [Escherichia coli O157:H7 str. TW14359], g... gi\|191169257, gi... - gi\|75227458\|ref\|ZP_00714227.1\| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of ... gi\|218361826, gi... - gi\|218555058\|ref\|YP_002387971.1\| inositol monophosphatase [Escherichia coli IAI1], gi\|218361826\|emb\|... gi\|75237721, gi\|... - gi\|75237721\|ref\|ZP_00721737.1\| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of ... gi\|218696160, gi... - gi\|218696160\|ref\|YP_002403827.1\| inositol monophosphatase [Escherichia coli 55989], gi\|218352892\|emb... gi\|75257957, gi\|... - gi\|75257957\|ref\|ZP_00729431.1\| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of ... gi\|218428217, gi... - gi\|218690653\|ref\|YP_002398865.1\| inositol monophosphatase [Escherichia coli ED1a], gi\|218428217\|emb\|... SUHB_ECOLI - Inositol-1-monophosphatase (EC 3.1.3.25) (IMPase) (Inositol-1-phosphatase) (I-1-Pase) - Escherichia ...	1.0E-67	[8..280]	[1..260]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLTRQVLEE VENTFIELLR SKIGPLVKSH AGTNFCSYDD KANGVDLVTA LDKQIESIIK  60
   61 ENLTAKYPSF KFIGEETYVK GVTKITNGPT FIVDPIDGTT NFIHGYPYSC TSLGLAEMGK 120
  121 PVVGVVFNPH LNQLFHASKG NGAFLNDQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	469.68867
Match:	1imaA_
Description:	Inositol monophosphatase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [149-292]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EIKVSKRPLI LQKSLIALEG GSERTEGSQG NFDKKMNTYK NLLSESGAFV HGFRSAGSAA  60
   61 MNICYVASGM LDAYWEGGCW AWDVCAGWCI LEEAGGIMVG GNCGEWNIPL DRRCYLAIRG 120
  121 GCESMEQKRF AESFWPHVAG ELEY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	469.68867
Match:	1imaA_
Description:	Inositol monophosphatase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits