Protein Overview: RAV2

General Information:
Name(s) found:	RAV2 / YDR202C [SGD]
Description(s) found: Found 32 descriptions. SHOW ALL	Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme [SGD]
Organism:	Saccharomyces cerevisiae
Length:	351 amino acids
Gene Ontology:
Cellular Component:	RAVE complex [IPI]
Biological Process:	regulation of protein complex assembly [IGI ][IMP][IPI] vacuolar acidification [IGI ][IMP ]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVDLFPNDR FGAEDKYDNF KDAVKECSWL IEEIVKPQLP NIIDNFSKCL EMLESDQIFK  60
   61 MPVSNGIPNE SNKQNDSPTV KGVITRQGQY IVDFHIVVRF PQFQRGKQVM FRMNTGLNFL 120
  121 LIQFSKIMTH LKNILEILNQ LQVATDVSEF VSKFGVAMEL LNHSLILLQN PPRDLVFPED 180
  181 NNFAMKEMFQ DCYSVCESTA HILGLELTLC RNELCIELRN LIKVTKKPWC EIDSKTGRSF 240
  241 CDQIRNQVTN ERNKTLSKIL SENGVQVQDS TLLNHIISSF QSEAITLPEA QELLRRGVTF 300
  301 DNRVVMECEK LIVSTSDPTL ISISAKLNSL KASMANHQAN LVASKQLSTY K

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		RAV1 RAV2
View Details	Qiu et al. (2008)		RAV1 RAV2 SKP1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PCF11	RAV2	1	Unpublished Fields Lab Data
View Screen	UBP6	RAV2	1	Unpublished Fields Lab Data
View Screen	UBC7	RAV2	1	Unpublished Fields Lab Data
View Screen	PHO85	RAV2	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	RAV2	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..351]	deduced	N/A	No confident structure predictions are available.
2	View Details	[77..351]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2