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Protein Overview: RGP1

General Information:
Name(s) found: RGP1 / YDR137W [SGD]
Description(s) found:
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  • gi|665670|emb|CAA88219.1| Rgp1p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6320340|ref|NP_010421.1| Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p; Rgp1p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|2507111|sp|P16664.2|RGP1_YEAST RecName: Full=Reduced growth phenotype protein 1 [NCBI NR]
  • pir||S51865 RGP1 protein - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Reduced growth phenotype protein 1 OS=Saccharomyces cerevisiae GN=RGP1 PE=1 SV=2 [Swiss-Prot]
  • RGP1 Reduced growth phenotype protein [mips]
  • Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p [SGD]
  • RGP1, Chr IV from 728252-730243 [yeast_orfs2]
  • Chr IV from 728252-730243 [yeastorf3.fasta]
  • (P16664) Reduced growth phenotype protein (RGP1 protein) [4932.FASTACCERV.txt]
  • RGP1 SGDID:S0002544, Chr IV from 728253-730244, Verified ORF [yeastflysequest.fasta]
  • RGP1 SGDID:S0002544, Chr IV from 728254-730245, Verified ORF [10112005cervSGD.fasta]
  • Rgp1p [Saccharomyces cerevisiae]gi|665670|emb|CAA88219.1| Rgp1p [Saccharomyces cerevisiae]gi|1078331|pir||S51865 RGP1 protein - yeast (Saccharomyces cerevisiae)gi|2507111|sp|P16664|RGP1_YEAST REDUCED GROWTH PHENOTYPE PROTEIN (RGP1 PROTEIN) [nrdb_11152004_Chlamydomonas]
  • RGP1 SGDID:S000002544, Chr IV from 728254-730245, Verified ORF, "Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • RGP1 SGDID:S000002544, Chr IV from 728256-730247, Verified ORF, "Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p" [yeast-contam.fasta]
  • RGP1 SGDID:S000002544, Chr IV from 728257-730248, Verified ORF, "Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • Reduced growth phenotype protein (Protein RGP1) [nr-271106-contam.fasta]
  • Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p; Rgp1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Rgp1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Reduced growth phenotype protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RGP1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • RGP1 SGDID:S000002544, Chr IV from 728259-730250, Genome Release 64-1-1, Verified ORF, "Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p" [yeast-030211-contam.fasta]
  • RGP1 SGDID:S000002544, Chr IV from 728259-730250, Genome Release 64-2-1, Verified ORF, "Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p); this complex catalyzes nucleotide exchange on Ypt6p" [20141208_orf_trans.fasta]
  • YDR137W SGDID:S000002544, Chr IV from 728259-730250, Genome Release 64-1-1, Verified ORF, "Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • Guanine nucleotide exchange factor subunit RGP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RGP1 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Saccharomyces cerevisiae
    Length: 663 amino acids

    Gene Ontology:
    Cellular Component: Golgi membrane [IPILink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    guanyl-nucleotide exchange factor complex [IDALink to PubMed article]
    Biological Process: retrograde transport, endosome to Golgi [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: guanyl-nucleotide exchange factor activity [IDALink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAHRIDTFL IRENIKLEII HESNSYFGGE HISIAFRFKH LGSQHELFNY KEKLLTVDKA  60
   61 VEEKLEQQAK VQDDGEGTME NQTWSLKSLL GAFKRTGEPE ESVDVDNMKM LNESKMLREK 120
  121 IQKQMYFHQP VTLISGYVQI SGVFQYDSEV ISESKFKQDE VKMVGLDIVP GHTTNSVLAL 180
  181 EDGEHFKGKR NLTNYLNSDY TNVTNGLLFS ESGSRGRTGT YNERTLMISN DTSIKTLPLL 240
  241 LIPQTLLFSE ISLEPGEVRT FYFKSTKLPK DICPSYSSSK VASINYTLEV GADVLSDDNI 300
  301 EKFSNRVPIT IAPYISSNAE QYTSRLDKPA IILKTGNIKE LKPRLFTRKV STASAVSFGR 360
  361 RKSSIIDIDS PLEDNEFVKR VKKNFIELVE SNQNVSRDID ELIDLQMGVQ FGKDEDSSDP 420
  421 EPNDSHFSNE MVTSAESSLR SDAVTKRRKS YSVRDNISNL EQKMWNDCSL VKSDENSNLL 480
  481 PQLINLQNAY QINRNNETMA KVSLSAPFYK TTDDINLVIE LDPITTPLLK VTSLTVSLES 540
  541 FEIINPKYKT EGKGIGSKPK GNSVYEKHFI CFDECKSVSV KLLPPRSPTN QITGQFKTDV 600
  601 FQHKWMIGLK FVIIAKTESI TLDQFYEDKK GILFHSKENL EGEEFTCYVP IPILCTSEDF 660
  661 MGW

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) RGP1 RIC1
    View Details Krogan NJ, et al. (2006) RGP1 RIC1 SYG1 YIP3
    View Details Gavin AC, et al. (2006) RGP1 RIC1
    View Details Ho Y, et al. (2002) GDI1 RGP1 RIC1 YPT6
    View Details Qiu et al. (2008) RGP1 RIC1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TID3 No Comments Cheeseman IM, et al. (2002)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RGP1 Huh WK, et al. (2003)
    View Data RGP1 and COP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..187] deduced N/A No confident structure predictions are available.
    2 View Details [188..350] MSA 2.005984 View MSA. No confident structure predictions are available.
    3 View Details [351..455] deduced N/A No confident structure predictions are available.
    4 View Details [456..663] MSA 3.005968 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle