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Protein Overview: COS7

General Information:
Name(s) found: COS7 / YDL248W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 383 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: receptor activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKENEVKDEK SVDVLSFKQL ESQKIVLPQD LFRSSFTWFC YEIYKSLAFR IWMLLWLPLS  60
   61 VWWKLSNNCI YPLIVSLLVL FLGPIFVLVI CGLSRKRSLS KQLIQFCKEI TENTPSSDPH 120
  121 DWEVVVANLN SYLYENKAWN TKNFFFNATD CEKMFRTTVL EPFSLKKDKA AKVKSFKDSV 180
  181 PYIEEALQVY ATGFDKQWKL FITEKSWSPV GLEDVQLPKD IHRSKLTWFL KRIFTIYSLP 240
  241 LWLAFLNCIC VSQHFCLAFR ILCPGLFFLM MVWLFQNMRT TALLVKMEHK MQFLLTIINE 300
  301 QESGANGWDE IARKMNRYLF EKKAWKNEEF FFDGIDCEWF FSHFFYRLLS AKKSMWLLPL 360
  361 NVELWPYIKE AQLSRNEESL MKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) COS2, COS3 COS7

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data COS7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..61] MSA 1.018984 View MSA. No confident structure predictions are available.
    2 View Details [62..173] Pfam 48.39794 DUP family Confident ab initio structure predictions are available.
    3 View Details [174..244] deduced N/A No confident structure predictions are available.
    4 View Details [245..383] Pfam 59.886057 DUP family No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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