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View Structure Prediction Details

Protein: COS7
Organism: Saccharomyces cerevisiae
Length: 383 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS7.

Description E-value Query
Range
Subject
Range
COS5 - Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encode...
COS5_YEAST - Protein COS5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COS5 PE=1 SV=1
604.0 [0..1] [383..1]

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Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKENEVKDEK SVDVLSFKQL ESQKIVLPQD LFRSSFTWFC YEIYKSLAFR IWMLLWLPLS  60
   61 V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [62-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WWKLSNNCIY PLIVSLLVLF LGPIFVLVIC GLSRKRSLSK QLIQFCKEIT ENTPSSDPHD  60
   61 WEVVVANLNS YLYENKAWNT KNFFFNATDC EKMFRTTVLE PFSLKKDKAA KV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 48.39794
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.934 N/A N/A a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #3
Region A:
Residues: [174-244]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSFKDSVPYI EEALQVYATG FDKQWKLFIT EKSWSPVGLE DVQLPKDIHR SKLTWFLKRI  60
   61 FTIYSLPLWL A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [245-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLNCICVSQH FCLAFRILCP GLFFLMMVWL FQNMRTTALL VKMEHKMQFL LTIINEQESG  60
   61 ANGWDEIARK MNRYLFEKKA WKNEEFFFDG IDCEWFFSHF FYRLLSAKKS MWLLPLNVEL 120
  121 WPYIKEAQLS RNEESLMKK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 59.886057
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle