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Protein Overview: COS5

General Information:
Name(s) found: COS5 / YJR161C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encoded proteins [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 383 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKENELKNEK SVDVLSFKQL ESQKIVLPQD LFRSSFTWFC YEIYKSLAFP IWMLLWLPLS  60
   61 VWWKLSNNCI YPLIVSLLVL FLGPIFVLVI CGLSRKRSLS KQLIQFCKEV TENTPSSDPH 120
  121 DWEVVAANLN SYLYENKAWN TRYFFFNAMG CQEAFRTTLL EPFSLKKDEA AKVKSFKDSV 180
  181 PYIEEALGVY FREVEKQWKL FNTEKSWSPV GLEDVQLPKD IHRSKLTWFL KRIFTIYSLP 240
  241 LWLAFLNCIC VSQHFCLAFR ILCPGLFFLM MVWLFQNMRT TALLVKMEHK MQFLLTIINE 300
  301 QESGANGWDE IARKMNRYLF EKKAWKNEEF FFEGIDCEWF FSHFFYRLLS AKKSMWLLPL 360
  361 NVELWPYIKE AQLSRNEESL MKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) COS2, COS3 COS5

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data COS5 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..61] MSA 1.017984 View MSA. No confident structure predictions are available.
    2 View Details [62..169] Pfam 52.275724 DUP family Confident ab initio structure predictions are available.
    3 View Details [170..222] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [223..383] Pfam 58.920819 DUP family No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle