YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: COS7
Organism: Saccharomyces cerevisiae
Length: 383 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS7.

Description E-value Query
Range
Subject
Range
COS5 - Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encode...
COS5_YEAST - Protein COS5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COS5 PE=1 SV=1
604.0 [0..1] [383..1]

Back

Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKENEVKDEK SVDVLSFKQL ESQKIVLPQD LFRSSFTWFC YEIYKSLAFR IWMLLWLPLS  60
   61 V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.477 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.458 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.426 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.405 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.400 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.358 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.357 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.354 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains

Predicted Domain #2
Region A:
Residues: [62-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WWKLSNNCIY PLIVSLLVLF LGPIFVLVIC GLSRKRSLSK QLIQFCKEIT ENTPSSDPHD  60
   61 WEVVVANLNS YLYENKAWNT KNFFFNATDC EKMFRTTVLE PFSLKKDKAA KV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 48.39794
Match: PF00674
Description: DUP family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.934 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.856 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.856 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.823 N/A N/A a.216.1 Description not found.
View Download 0.794 N/A N/A a.29.2 Bromodomain
View Download 0.780 N/A N/A a.19.1 Fertilization protein
View Download 0.780 N/A N/A a.19.1 Fertilization protein
View Download 0.766 N/A N/A a.29.13 Description not found.
View Download 0.707 N/A N/A a.29.2 Bromodomain
View Download 0.642 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins

Predicted Domain #3
Region A:
Residues: [174-244]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSFKDSVPYI EEALQVYATG FDKQWKLFIT EKSWSPVGLE DVQLPKDIHR SKLTWFLKRI  60
   61 FTIYSLPLWL A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.790 a.2.17 Description not found.
View Download 0.772 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.717 a.2.7 tRNA-binding arm
View Download 0.717 a.2.7 tRNA-binding arm
View Download 0.711 d.52.1 Alpha-lytic protease prodomain
View Download 0.700 d.52.1 Alpha-lytic protease prodomain
View Download 0.658 d.58.17 Metal-binding domain
View Download 0.621 d.58.17 Metal-binding domain
View Download 0.621 d.58.17 Metal-binding domain
View Download 0.595 d.58.17 Metal-binding domain

Predicted Domain #4
Region A:
Residues: [245-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLNCICVSQH FCLAFRILCP GLFFLMMVWL FQNMRTTALL VKMEHKMQFL LTIINEQESG  60
   61 ANGWDEIARK MNRYLFEKKA WKNEEFFFDG IDCEWFFSHF FYRLLSAKKS MWLLPLNVEL 120
  121 WPYIKEAQLS RNEESLMKK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 59.886057
Match: PF00674
Description: DUP family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.554 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.406 N/A N/A a.70.2 Description not found.
View Download 0.297 N/A N/A a.118.1 ARM repeat
View Download 0.288 N/A N/A d.162.1 LDH C-terminal domain-like
View Download 0.284 N/A N/A f.39.1 Description not found.
View Download 0.283 N/A N/A d.162.1 LDH C-terminal domain-like
View Download 0.280 N/A N/A d.162.1 LDH C-terminal domain-like
View Download 0.250 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.240 N/A N/A a.1.1 Globin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle