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Protein Overview: MGT1

General Information:
Name(s) found: MGT1 / YDL200C [SGD]
Description(s) found:
Found 21 descriptions.
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  • DNA repair methyltransferase (6-O-methylguanine-DNA methylase) involved in protection against DNA alkylation damage [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 206 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    Biological Process: DNA dealkylation involved in DNA repair [IMPLink to PubMed article]
    Molecular Function: methylated-DNA-[protein]-cysteine S-methyltransferase activity [IDALink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKKKIENGR IFDLNGPTMK ELLYYTFIET EVTGAFLVFR EKTQNLVFAS LGNDKLFLLG  60
   61 KVEGFLKKHE KQDTMYDLQE LKEAETYKKS IENYTICLEN KMPLPSGAIP FEFLFGTDFQ 120
  121 RKVWNELLNV EHGHVVTYGD IAKRIGKPTA ARSVGRACGS NNLALLVPCH RIVGSNRKLT 180
  181 GYKWSCKLKE QLLNNEKENS LSLSRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] PSI-BLAST 232.69897 Ada DNA repair protein
    2 View Details [115..206] PSI-BLAST 232.69897 Ada DNA repair protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methylated-DNA-[protein]-cysteine S-methyltransferase activity
    		•  3.81641972619245 bayes_pls_golite062009
  • S-methyltransferase activity
    		•  2.66007025371147 bayes_pls_golite062009
  • catalytic activity
    		•  1.90838528948382 bayes_pls_golite062009
  • DNA binding
    		•  1.54553435062678 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.49720271661049 bayes_pls_golite062009
  • binding
    		•  1.30758209326705 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.26332746912934 bayes_pls_golite062009
  • transferase activity
    		•  1.22815682532854 bayes_pls_golite062009
  • methyltransferase activity
    		•  1.14625481859451 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  1.13184530961695 bayes_pls_golite062009
  • transcription factor activity
    		•  0.99095733801135 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle