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Protein Overview: CRD1

General Information:
Name(s) found: CRD1 / YDL142C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 283 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial envelope [IDALink to PubMed article]
    Biological Process: lipid biosynthetic process [IDALink to PubMed article][IMPLink to PubMed article]
    mitochondrial membrane organization [IMPLink to PubMed article]
    Molecular Function: cardiolipin synthase activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQMVPIYSC SALLRRTIPK RPFYHVLSGL TVRFKVNPQL NYNLFRDLTR REYATNPSKT  60
   61 PHIKSKLLNI PNILTLSRIG CTPFIGLFII TNNLTPALGL FAFSSITDFM DGYIARKYGL 120
  121 KTIAGTILDP LADKLLMITT TLALSVPSGP QIIPVSIAAI ILGRDVLLAI SALFIRYSTL 180
  181 KLKYPGRVAW NSYWDIVRYP SAEVRPSQLS KWNTFFQMVY LGSGVLLLLY EKEEGCEKTE 240
  241 EDFEDRKQDF QKAFSYLGYV TATTTIMSGV SYALKRNAFK LLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen KAP104 CRD1 1 Unpublished Fields Lab Data
    View Screen RRB1 CRD1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CRD1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..58] deduced N/A No confident structure predictions are available.
    2 View Details [59..283] Pfam 28.585027 CDP-alcohol phosphatidyltransferase No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle