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Protein Overview: PBN1

General Information:
Name(s) found: PBN1 / YCL052C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Essential component of glycosylphosphatidylinositol-mannosyltransferase I, required for the autocatalytic post-translational processing of the protease B precursor Prb1p, localizes to ER in lumenal orientation; homolog of mammalian PIG-X [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 416 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: GPI anchor biosynthetic process [IMPLink to PubMed article]
    protein processing [IMPLink to PubMed article]
    ER-associated protein catabolic process [IMPLink to PubMed article]
    Molecular Function: mannosyltransferase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTRHRVTVL YNAPEDIGNH MRQNDTHLTV RGGSGVVLQQ RWLLERTGSL DKSFTRITWR  60
   61 PRADLARSLS VIENELSAGF SVYSNSSDVP ERFITNPVYN SFHSEKFDIE QYLPPEVDLN 120
  121 LSWNPEDFTY DISVEPTQIQ IVEYRLLKQG EEFTIARVKD EKLEVGVFFV DASDESDVDI 180
  181 GGIRCNWRMD DGKMERCQKT SLLYKQGHIA YNHSTTTTSL YLNEPIGLHP KIMIDLTDFE 240
  241 ERPKCMYLMH LQLPLELFID KFQSSPLLLF GEDDLELPEY SLRDKAWGSE SIFELKAGTM 300
  301 NEVTLHTRYI EPSNNKGDKL EVSFDPEVIL ACDTGDNKVS RNPFYKKGLG YESLFTDDTT 360
  361 FRHLNSTTLL VPIPRPDTKD YSKIKNGTLL CLLISIIYIF SKVFGNNKKK RSVKRE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PBN1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..174] deduced N/A No confident structure predictions are available.
    2 View Details [175..416] Pfam 101.920819 No description for PF08320.3 was found. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.50

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle