Protein Overview: FUS1

General Information:
Name(s) found:	FUS1 / YCL027W [SGD]
Description(s) found: Found 25 descriptions. SHOW ALL	Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate [SGD]
Organism:	Saccharomyces cerevisiae
Length:	512 amino acids
Gene Ontology:
Cellular Component:	mating projection tip [IDA] plasma membrane [IDA]
Biological Process:	conjugation with cellular fusion [IMP] regulation of termination of mating projection growth [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVATIMQTTT TVLTTVAAMS TTLASNYISS QASSSTSVTT VTTIATSIRS TPSNLLFSNV  60
   61 AAQPKSSSAS TIGLSIGLPI GIFCFGLLIL LCYFYLKRNS VSISNPPMSA TIPREEEYCR 120
  121 RTNWFSRLFW QSKCEDQNSY SNRDIEKYND TQWTSGDNMS SKIQYKISKP IIPQHILTPK 180
  181 KTVKNPYAWS GKNISLDPKV NEMEEEKVVD AFLYTKPPNI VHIESSMPSY NDLPSQKTVS 240
  241 SKKTALKTSE KWSYESPLSR WFLRGSTYFK DYGLSKTSLK TPTGAPQLKQ MKMLSRISKG 300
  301 YFNESDIMPD ERSPILEYNN TPLDANDSVN NLGNTTPDSQ ITSYRNNNID LITARPHSVI 360
  361 YGTTAQQTLE TNFNDHHDCN KSTEKHELII PTPSKPLKKR KKRRQSKMYQ HLQHLSRSKP 420
  421 LPLTPNSKYN GEASVQLGKT YTVIQDYEPR LTDEIRISLG EKVKILATHT DGWCLVEKCN 480
  481 TQKGSIHVSV DDKRYLNEDR GIVPGDCLQE YD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	IQG1	FUS1	2	Unpublished Fields Lab Data
View Screen	FUS1	YIR014W	2	Unpublished Fields Lab Data
View Screen	FUS1	SML1	2	Unpublished Fields Lab Data
View Screen	FUS1	HSP32	1	Unpublished Fields Lab Data
View Screen	FUS1	HAA1	1	Unpublished Fields Lab Data
View Screen	YLR224W	FUS1	1	Unpublished Fields Lab Data
View Screen	SPT21	FUS1	1	Unpublished Fields Lab Data
View Screen	FUS1	CDC36	1	Unpublished Fields Lab Data
View Screen	FUS1	YDL199C	1	Unpublished Fields Lab Data
View Screen	FUS1	MSB2	1	Unpublished Fields Lab Data
View Screen	FUS1	BFA1	1	Unpublished Fields Lab Data
View Screen	FUS1	PAU19	1	Unpublished Fields Lab Data
View Screen	FUS1	RPS28A	1	Unpublished Fields Lab Data
View Screen	FUS1	GRE1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	FUS1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..430]	deduced	N/A	No confident structure predictions are available.
2	View Details	[431..512]	Pfam	3.638272	SH3 domain No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2