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Protein Overview: SAF1

General Information:
Name(s) found: SAF1 / YBR280C [SGD]
Description(s) found:
Found 15 descriptions.
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  • F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 642 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKHIMSEVE SREKEPDAGL SPDIVQATLP FLSSDDIKNL SQTNKYYNTL LDFDHSKILW  60
   61 HELFHKAFGT LKTNDEPFQG RNSAEFKTCT ETILREAFPT LSWQEVYQLR AYDAKFYSWG 120
  121 YLKHGRLGYT ASSNNELVAT SLNGPSPRFK YGVNTPTEVP WFNSRTTSRT SNFTPSEDPL 180
  181 SAIKKDGDEI IAQVSSGGFS FQILTESGNL YSSGSTFSGG LKGPGPSGSQ HDYNPFREMI 240
  241 HNMERSYPRI TSRSNGSTVN TTGTFSGRRM SGSHPSTAYE PGNATTAQHI TIDSGGAPAA 300
  301 SPGGSHSGVP RTTMPSMGPH ENIYSQIEML ERSANKAVPG NNHIRRMFAR NSFPLYSGRD 360
  361 ENLGSFNDIQ FVAVSSGRSH FLAMDTDNNI YSWDSTESDQ GVKIEFANLP SRATNPILKI 420
  421 ASGWNFNCCY IYKVGLVAWK ERDAIQKGES FAFAKYEIVP NTNDVNGDSR IVDFACLQDN 480
  481 CVFFINNNGD KLWKYHNGLN QIVDLNIVGK LCKINACFAS LVLFTDTHCY TLKVTNGDVD 540
  541 KDSLTELDIN ENVISVASGD YHTVALTERG HLYSWGIESQ DCGCLGLGPS EKIVNELHIG 600
  601 NWEGQRNIRV VKPTKIELPE DYICVSVTAG GWQTGALIIK KH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..287] deduced N/A No confident structure predictions are available.
    2 View Details [288..642] PSI-BLAST 75.68867 Regulator of chromosome condensation RCC1


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle