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View Structure Prediction Details

Protein: SAF1
Organism: Saccharomyces cerevisiae
Length: 642 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAF1.

Description E-value Query
Range
Subject
Range
gi|7488217, gi|7... - pir||F71405 probable TMV resistance protein - Arabidopsis thaliana, gi|7268142|emb|CAB78479.1| dise...
6.0E-71 [230..635] [1041..1540]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-67 [340..639] [3018..3327]
gi|12856817 - gi|12856817|dbj|BAB30794.1| unnamed protein product [Mus musculus]
2.0E-64 [342..638] [52..378]
gi|10726982, gi|... - gi|24643485|ref|NP_608388.1| HERC2 [Drosophila melanogaster], gi|10726982|gb|AAF50913.2| HERC2 [Dros...
4.0E-64 [340..640] [4109..4416]
HERC3 - hect domain and RLD 3
gi|7657152 - ref|NP_055421.1| hect domain and RLD 3 [Homo sapiens]
gi|187252515, gi... - gi|187252515|gb|AAI66672.1| Hect domain and RLD 3 [synthetic construct], gi|168274306|dbj|BAG09573.1...
1.0E-63 [342..638] [52..378]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKHIMSEVE SREKEPDAGL SPDIVQATLP FLSSDDIKNL SQTNKYYNTL LDFDHSKILW  60
   61 HELFHKAFGT LKTNDEPFQG RNSAEFKTCT ETILREAFPT LSWQEVYQLR AYDAKFYSWG 120
  121 YLKHGRLGYT ASSNNELVAT SLNGPSPRFK YGVNTPTEVP WFNSRTTSRT SNFTPSEDPL 180
  181 SAIKKDGDEI IAQVSSGGFS FQILTESGNL YSSGSTFSGG LKGPGPSGSQ HDYNPFREMI 240
  241 HNMERSYPRI TSRSNGSTVN TTGTFSGRRM SGSHPSTAYE PGNATTA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [288-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHITIDSGGA PAASPGGSHS GVPRTTMPSM GPHENIYSQI EMLERSANKA VPGNNHIRRM  60
   61 FARNSFPLYS GRDENLGSFN DIQFVAVSSG RSHFLAMDTD NNIYSWDSTE SDQGVKIEFA 120
  121 NLPSRATNPI LKIASGWNFN CCYIYKVGLV AWKERDAIQK GESFAFAKYE IVPNTNDVNG 180
  181 DSRIVDFACL QDNCVFFINN NGDKLWKYHN GLNQIVDLNI VGKLCKINAC FASLVLFTDT 240
  241 HCYTLKVTNG DVDKDSLTEL DINENVISVA SGDYHTVALT ERGHLYSWGI ESQDCGCLGL 300
  301 GPSEKIVNEL HIGNWEGQRN IRVVKPTKIE LPEDYICVSV TAGGWQTGAL IIKKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.68867
Match: 1a12A_
Description: Regulator of chromosome condensation RCC1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle