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Protein Overview: RIB1

General Information:
Name(s) found: RIB1 / YBL033C [SGD]
Description(s) found:
Found 25 descriptions.
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  • GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 345 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: riboflavin biosynthetic process [IMPLink to PubMed articleLink to PubMed article]
    response to drug [IMPLink to PubMed article]
    Molecular Function: cyclohydrolase activity [IGILink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIDNYDNSK QDSSKYEVSG TGDGRNGDGG LPLVQCVARA RIPTTQGPDI FLHLYSNNRD  60
   61 NKEHLAIVFG EDIRSRSLFR RRQCETQQDR MIRGAYIGKL YPGRTVADED DRLGLALEFD 120
  121 DSTGELLASK ATTWDAHNDT LVRIHSECYT GENAWSARCD CGEQFDRAGR LIACDHEPTS 180
  181 NIKGGNGHGV IVYLRQEGRG IGLGEKLKAY NLQDLGADTV QANLMLKHPV DARDFSLGKA 240
  241 ILLDLGIGNV RLLTNNPEKI KQVDHAPYLK CVERVPMVPI HWTNSSEGID SKEIEGYLRT 300
  301 KIERMGHLLT EPLKLHTNPQ PTETSEAQNQ NRMNSALSST STLAI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RIB1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] PSI-BLAST 5.69897 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
    2 View Details [135..186] deduced N/A No confident structure predictions are available.
    3 View Details [187..345] MSA 1.073971 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • GTP cyclohydrolase activity
    		•  4.36867535385235 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  3.7708397651039 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  3.33696578638249 bayes_pls_golite062009
  • catalytic activity
    		•  1.40764037338379 bayes_pls_golite062009
  • binding
    		•  1.36587778604607 bayes_pls_golite062009
  • protein binding
    		•  0.182596805520355 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle