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Protein Overview: SWH1

General Information:
Name(s) found: SWH1 / YAR042W [SGD]
Description(s) found:
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  • SWH1 - similarity to mammalian oxysterol-binding proteins [mips]
  • Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the Golgi and the nucleus-vacuole junction [SGD]
  • SWH1, Chr I from 192609-193379 [yeast_orfs2]
  • Chr I from 192609-193379 [yeastorf3.fasta]
  • Chr I from 192613-193383 [yeastorf4.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 256 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    early endosome [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Golgi trans cisterna [IDALink to PubMed article]
    Biological Process: sterol transport [IGILink to PubMed article]
    endocytosis [IGILink to PubMed article]
    exocytosis [IGILink to PubMed article]
    Molecular Function: oxysterol binding [ISSLink to PubMed article]
    phosphatidylinositol binding [ISSLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQPDLSSVA ISKPLLKLKL LDALRQGSFP NLQDLLKKQF QPLDDPNVQQ VLHLMLHYAV  60
   61 QVAPMAVIKE IVHHWVSTTN TTFLNIHLDL NERDSNGNTP LHIAAYQSRG DIVAFLLDQP 120
  121 TINDCVLNNS HLQAIEMCKN LNIAQMMQVK RSTYVAETAQ EFRTAFNNRD FGHLESILSS 180
  181 PRNAELLDIN GMDPETGDTV LHEFVKKRDV IMCRWLLEHG ADPFKRDRKA NCPSSSLGKS 240
  241 MKTTPPPAPR SPSTSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..121] PSI-BLAST 38.154902 bcl-3
    2 View Details [122..256] PSI-BLAST 38.154902 bcl-3


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle