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Protein Overview: FUN26

General Information:
Name(s) found: FUN26 / YAL022C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Nucleoside transporter with broad nucleoside selectivity; localized to intracellular membranes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 517 amino acids

    Gene Ontology:
    Cellular Component: membrane [IDALink to PubMed article]
    intracellular [IDALink to PubMed article]
    Biological Process: nucleoside transport [IDALink to PubMed article]
    Molecular Function: nucleoside transmembrane transporter activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSADTDTI KKPILAVPEP ALADTHSEEI SRSGEEHESE NNEHSDEEGD NYSEREQSVS  60
   61 TEPLDTLPLR KKLKNLSYIT FFAIGIGLLW PWNCILSASQ YFKHDIFKDT SIWAKIFTSS 120
  121 MMSFSTISSM LFNIYLAKRQ YKYSRRVING LVWEIIVFTV MCFFTILHFL LPKWFNFMFI 180
  181 MMLVVISSMG TAMTQNGIMA IANVFGSEYS QGVMVGQAVA GVLPSLVLFA LAFIENSSVS 240
  241 TTGGILLYFF TTTLVVTICV VMFSVSKISR KVNENWNVED GHITDVLLGS LRSNEEEIRI 300
  301 VGRIDQMEDE DHRRTNGTRD DNDEGEELQL KVPFEVLFAK LKYLVLSIFT TFVVTLVFPV 360
  361 FASATYVTGL PLSNAQYIPL IFTLWNLGDL YGRVIADWPM FRDQKFTPRK TFIYSLLRVA 420
  421 AIPLFLMFTA ITSSSSGDEE HNGSVIVDLC YMLLQFLFGV TNGHVISMSF MKVPEQLDND 480
  481 DEKEAAGGFT NIFVSTGLAL GSIISYVFVF IIDFIIR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) FCY2 FUN26

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #19b Asynchronous Prep1-new search criteria Keck JM, et al. (2011)
    View Run MLP2 #19a Asynchronous Prep1-new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] MSA 1.047986 View MSA. No confident structure predictions are available.
    2 View Details [172..517] Pfam 173.619789 Nucleoside transporter No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  3.82096685159505 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.34396155292818 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.07161916881404 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.00564985710417 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.75140121218978 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.46819549608723 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.34985844043603 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  0.869150152038001 bayes_pls_golite062009
  • binding
    		•  0.67385346756555 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.339747214378126 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.339747214378126 bayes_pls_golite062009
  • symporter activity
    		•  0.327558013224678 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.327558013224678 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.222664452597504 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle