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View Structure Prediction Details

Protein: FUN26
Organism: Saccharomyces cerevisiae
Length: 517 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUN26.

Description E-value Query
Range
Subject
Range
FUN26 - Nucleoside transporter with broad nucleoside selectivity; localized to intracellular membranes
gi|190406670 - gi|190406670|gb|EDV09937.1| nucleoside transporter FUN26 [Saccharomyces cerevisiae RM11-1a]
gi|207348009 - gi|207348009|gb|EDZ73995.1| YAL022Cp-like protein [Saccharomyces cerevisiae AWRI1631]
FUN26_YEAST - Nucleoside transporter FUN26 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FUN26 PE=1 ...
0.0 [1..517] [1..517]
S29A2_RAT - Equilibrative nucleoside transporter 2 OS=Rattus norvegicus GN=Slc29a2 PE=2 SV=1
0.0 [68..512] [5..456]
gi|8568092 - gi|8568092|gb|AAF76431.1|AF257190_1 NBMPR-insensitive equilibrative nucleoside transporter [mouse/ra...
S29A2_MOUSE - Equilibrative nucleoside transporter 2 OS=Mus musculus GN=Slc29a2 PE=1 SV=2
0.0 [68..512] [5..456]
gi|130489840, gi... - gi|130489840|ref|NP_001076159.1| solute carrier family 29 (nucleoside transporters), member 2 [Oryct...
0.0 [69..512] [6..456]
S29A4_MOUSE - Equilibrative nucleoside transporter 4 OS=Mus musculus GN=Slc29a4 PE=1 SV=1
2.0E-98 [19..506] [11..498]
gi|3450834 - gi|3450834|gb|AAC32597.1| nucleoside transporter 1.1 [Leishmania donovani]
5.0E-97 [48..505] [1..481]
gi|19401672 - gi|19401672|gb|AAL87658.1|AF452412_1 adenosine permease [Leishmania mexicana amazonensis]
3.0E-94 [48..505] [1..481]

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Predicted Domain #1
Region A:
Residues: [1-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSADTDTI KKPILAVPEP ALADTHSEEI SRSGEEHESE NNEHSDEEGD NYSEREQSVS  60
   61 TEPLDTLPLR KKLKNLSYIT FFAIGIGLLW PWNCILSASQ YFKHDIFKDT SIWAKIFTSS 120
  121 MMSFSTISSM LFNIYLAKRQ YKYSRRVING LVWEIIVFTV MCFFTILHFL L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transporter activity 3.82096685159505 bayes_pls_golite062009
transmembrane transporter activity 3.34396155292818 bayes_pls_golite062009
substrate-specific transporter activity 3.07161916881404 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.00564985710417 bayes_pls_golite062009
ion transmembrane transporter activity 1.75140121218978 bayes_pls_golite062009
active transmembrane transporter activity 1.46819549608723 bayes_pls_golite062009
cation transmembrane transporter activity 1.34985844043603 bayes_pls_golite062009
secondary active transmembrane transporter activity 0.869150152038001 bayes_pls_golite062009
binding 0.67385346756555 bayes_pls_golite062009
polyol transmembrane transporter activity 0.339747214378126 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.339747214378126 bayes_pls_golite062009
symporter activity 0.327558013224678 bayes_pls_golite062009
solute:cation symporter activity 0.327558013224678 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.222664452597504 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [172-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKWFNFMFIM MLVVISSMGT AMTQNGIMAI ANVFGSEYSQ GVMVGQAVAG VLPSLVLFAL  60
   61 AFIENSSVST TGGILLYFFT TTLVVTICVV MFSVSKISRK VNENWNVEDG HITDVLLGSL 120
  121 RSNEEEIRIV GRIDQMEDED HRRTNGTRDD NDEGEELQLK VPFEVLFAKL KYLVLSIFTT 180
  181 FVVTLVFPVF ASATYVTGLP LSNAQYIPLI FTLWNLGDLY GRVIADWPMF RDQKFTPRKT 240
  241 FIYSLLRVAA IPLFLMFTAI TSSSSGDEEH NGSVIVDLCY MLLQFLFGVT NGHVISMSFM 300
  301 KVPEQLDNDD EKEAAGGFTN IFVSTGLALG SIISYVFVFI IDFIIR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 173.619789
Match: PF01733
Description: Nucleoside transporter

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle