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Protein Overview: BI2

General Information:
Name(s) found: BI2 / Q0110 [SGD]
Description(s) found:
Found 22 descriptions.
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  • Mitochondrial mRNA maturase with a role in splicing, encoded by both exon and intron sequences of partially processed COB mRNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 423 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [TASLink to PubMed article]
    Biological Process: RNA splicing [IDALink to PubMed article]
    Molecular Function: nuclease activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFRKSNVYL SLVNSYIIDS PQPSSINYWW NMGSLLGLCL VIQIVTGIFM AMHYSSNIEL  60
   61 AFSSVEHIMR DVHNGYILRY LHANGASFFF MVMFMHMAKG LYYGSYRSPR VTLWNVGVII 120
  121 FILTIATAFL GYCCVYGQMS HWGNMNIASN MFNMMKTIYM MMLMLLIYIF YTIMMRQMMK 180
  181 TKEYTMLIKS MDYINKNKYM INLNMTNKKD MNNNIGPLNM NILSIIYGSM LGDGHAEKRK 240
  241 GGKGTRIVFQ QEYCNINYLY YLHSLLANLG YCNTNLPLIK TRLGKKGKIR QYLKFNTWTY 300
  301 DSFNMIYSEW YIKNMSGKGN IKVIPKSLDN YLTPLALAIW IMDDGCKLGK GLKFTTNCFS 360
  361 YKDVQYLTYL LHNKYNIKST ITKGNKENTQ FVIYVWKESM PILTKIVSPY IIPSMKYKLG 420
  421 NYL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ACB1 ADE13 BI2 FRE7 KNS1 NUP170 STE2
    View Details Qiu et al. (2008) AI2 AI4 BI2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..226] PSI-BLAST 74.221849 Mitochondrial cytochrome b subunit, C-terminal domain; Mitochondrial cytochrome b subunit, N-terminal domain
    2 View Details [227..423] PSI-BLAST 40.69897 The homing endonuclease I-SceI bound to its DNA recognition region

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  1.62455464384151 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.44414324085777 bayes_pls_golite062009
  • catalytic activity
    		•  1.19342057724506 bayes_pls_golite062009
  • ubiquinol-cytochrome-c reductase activity
    		•  0.920386157101126 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  0.920386157101126 bayes_pls_golite062009
  • binding
    		•  0.774901332897627 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  0.503121667101722 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.486633405379917 bayes_pls_golite062009
  • protein binding
    		•  0.129189339756749 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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