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Protein Overview: AI3

General Information:
Name(s) found: AI3 / Q0060 [SGD]
Description(s) found:
Found 13 descriptions.
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  • Endonuclease I-SceIII, encoded by a mobile group I intron within the mitochondrial COX1 gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 403 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [TASLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: endonuclease activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG NSQLFNVLVM  60
   61 PALIGGFGNQ KRYESNNNNN QVMENKEYNL KLNYDKLGPY LAGLIEGDGT ITVQNSSSMK 120
  121 KSKYRPLIVV VFKLEDLELA NYLCNLTKCG KVYKKINRNY VLWTIHDLKG VYTLLNIING 180
  181 YMRTPKYEAF VRGAEFMNNY INSTTITHNK LKNMDNIKIK PLDTSDIGSN AWLAGMTDAD 240
  241 GNFSINLMNG KNRSSRAMPY YCLELRQNYQ KNSNNNNINF SYFYIMSAIA TYFNVNLYSR 300
  301 ERNLNLLVST NNTYKTYYSY KVMVANTYKN IKVMEYFNKY SLLSSKHLDF LDWSKLVILI 360
  361 NNEGQSMKTN GSWELGMNLR KDYNKTRTTF TWSHLKNTYL ENK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #13 Mitotic Prep2-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] PSI-BLAST 44.522879 Mitochondrial cytochrome c oxidase, subunit I
    2 View Details [115..403] PSI-BLAST 16.154902 The structure and DNA recognition of a bifunctional homing endonuclease and group I intron splicing factor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nuclease activity
    		•  1.30590086180382 bayes_pls_golite062009
  • catalytic activity
    		•  1.00294942392567 bayes_pls_golite062009
  • binding
    		•  0.947409481120466 bayes_pls_golite062009
  • hydrolase activity
    		•  0.908706495902542 bayes_pls_golite062009
  • endonuclease activity
    		•  0.892525491806151 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.861094108940112 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.59572260756409 bayes_pls_golite062009
  • DNA binding
    		•  0.156232940245275 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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